tag:blogger.com,1999:blog-50531332062113961872024-02-19T02:56:57.354+01:00Funktionaalinen ravintoTässä blogissani on seikkoja terveellisistä ravintotekijöistä ja kehon luonnollisesta puolustuksesta, jota voi tukea terveellisen ravitsemuksen ja terveellisten elämäntapojen avulla.Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.comBlogger146125tag:blogger.com,1999:blog-5053133206211396187.post-5254233281165464242023-04-25T21:44:00.002+02:002023-04-25T21:46:20.879+02:00Luun uudismuodostukseen vaikuttavista öljyistä <p> <br /></p><div class="article-citation">
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<div class="journal-actions dropdown-block"><button aria-controls="full-view-journal" aria-expanded="false" aria-label="Toggle dropdown menu for journal Food & function" class="journal-actions-trigger trigger" data-pinger-ignore="" id="full-view-journal-trigger" tabindex="0" title="Food & function">
Food Funct
</button></div><span class="period">. </span><span class="cit">2020 Aug 19;11(8):7048-7060.</span>
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<span class="citation-doi">
doi: 10.1039/d0fo00884b.
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<h4 class="heading-title" style="text-align: left;">
The opposite effects of Antarctic krill oil and arachidonic acid-rich oil on bone resorption in ovariectomized mice
</h4>
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<span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Qiping Zhan" href="https://pubmed.ncbi.nlm.nih.gov/?term=Zhan+Q&cauthor_id=32813003">Qiping Zhan</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-1" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn and College of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China.">
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</a></sup><span class="comma">, </span></span><span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Yingying Tian" href="https://pubmed.ncbi.nlm.nih.gov/?term=Tian+Y&cauthor_id=32813003">Yingying Tian</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-2" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn and Marine Biomedical Research Institute of Qingdao, Qingdao 266100, China.">
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</a></sup><span class="comma">, </span></span><span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Lihua Han" href="https://pubmed.ncbi.nlm.nih.gov/?term=Han+L&cauthor_id=32813003">Lihua Han</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-3" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn.">
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</a></sup><span class="comma">, </span></span><span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Kai Wang" href="https://pubmed.ncbi.nlm.nih.gov/?term=Wang+K&cauthor_id=32813003">Kai Wang</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-3" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn.">
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</a></sup><span class="comma">, </span></span><span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Jingfeng Wang" href="https://pubmed.ncbi.nlm.nih.gov/?term=Wang+J&cauthor_id=32813003">Jingfeng Wang</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-3" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn.">
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</a></sup><span class="comma">, </span></span><span class="authors-list-item"><a class="full-name" data-ga-action="author_link" data-ga-category="search" data-ga-label="Changhu Xue" href="https://pubmed.ncbi.nlm.nih.gov/?term=Xue+C&cauthor_id=32813003">Changhu Xue</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" href="https://pubmed.ncbi.nlm.nih.gov/32813003/#affiliation-3" title="College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China. jfwang@ouc.edu.cn xuech@ouc.edu.cn.">
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Affiliations
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<ul class="identifiers" id="full-view-identifiers"><li>
<span class="identifier pubmed">
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PMID:
</span>
<b class="current-id" title="PubMed ID">32813003</b>
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</li><li>
<span class="identifier doi">
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DOI:
</span>
<a class="id-link" data-ga-action="DOI" data-ga-category="full_text" href="https://doi.org/10.1039/d0fo00884b" rel="noopener" target="_blank">
10.1039/d0fo00884b </a></span></li><li><span class="identifier doi"> </span> Osteoporosis, a chronic disease that affects over 200 million people
worldwide, presents a substantial medical and socioeconomic burden on
the modern society. However, long-term intake of diets supplemented with
different polyunsaturated fatty acids (PUFAs) can affect bone
metabolism; thus, this study investigated the comparative effects of
Antarctic krill oil (AKO, containing n-3 PUFAs) and arachidonic
acid-rich oil (AAO, containing n-6 PUFAs) on bone resorption in a mice
model of postmenopausal osteoporosis. Mice were orally administered with
AKO (200 mg kg-1) or AAO (220 mg kg-1) once daily for 30 days,
ovariectomized, followed by the continued administration of the
respective samples for 90 days. Biomechanical and histomorphometric
analyses revealed that AKO increased the bone mineral density (BMD) to
enhance the biomechanical properties by increasing the mineral
apposition rate and repairing the microstructure of the trabecular bone,
whereas AAO had the opposite effect. The fatty acid analysis of the
vertebra showed that AKO increased the n-3 PUFA (especially for DHA)
content, thereby decreasing the ratio of n-6/n-3 PUFAs, which was
negatively correlated with the BMD. However, AAO had the opposite effect
due to high amounts of arachidonic acid. To explore the underlying
mechanism responsible for these observations, we compared the classical
bone resorption OPG/RANKL/NF-κB pathway mediated by PGE2/EP4. The ratio
of n-6/n-3 PUFAs in the bone affected the production of PGE2, a factor
regulating the OPG/RANKL pathway, thereby regulating osteoclastogenesis
by stimulating the NF-κB pathway. The results of ELISA, qRT-PCR, and
western blot demonstrated that AKO reduced the secretion of PGE2 and the
expression of EP4, upregulating the ratio of OPG/RANKL in the bone,
thereby decreasing TRAF6 expression to inhibit the activation of the
NF-κB signaling pathway, and finally inhibiting the expression of
nuclear transcription factors (c-fos and NFATc1) to prevent excessive
osteoclastogenesis (TRACP, MMP-9, and Cath-K). Arachidonic acid is a
precursor of PGE2 synthesis. AAO showed the opposite trend through the
same pathway. Thus, AKO could significantly improve osteoporosis via the
OPG/RANKL/NF-κB pathway mediated by PGE2/EP4 to inhibit
osteoclastogenesis, whereas AAO aggravated osteoporosis via the same
pathway. This is the first study to systematically compare the effects
and mechanism of AKO and AAO in regulating bone resorption in
osteoporotic mice to support recommendations on fatty acid types in
dietary oils for an osteoporotic population.
</li></ul>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-1676926017022930452022-10-06T16:52:00.001+02:002022-10-06T16:52:07.854+02:00Santelipuun öljyä tutkittiin jo 1930 luvulla . Gustaf Komppa syntetisoi manteliöljymolekyylin. Suomalainen Tiedeakatemia syntyi myös <p><a href="https://luontoemo.fi/tuote/santelipuu-5-eteerinen-oljy/"> https://luontoemo.fi/tuote/santelipuu-5-eteerinen-oljy/</a></p><p> Vuonno 1935 Gustaf Komppa teki tutkimuksensa Helsingin Tiedeakatemiass santelipuun öljyistä.
</p><ul><li><p><a name="multiVolumeLinkVolumes92"></a>Komppa, Gustaf
[VerfasserIn]; Nyman, Gustaf Arthur [VerfasserIn] <br />
Helsinki:
<a href="https://katalog.slub-dresden.de/id/0-1186730366">Über die
stereoisomeren Santenone und Santenole von Gust. Komppa und G. A.
Nyman </a>
Helsinki, Suomalainen
Tiedeakatemia, 1935 </p><p>HAKU Gustaf Komppa, 1935</p><div class="Z26q7c UK95Uc" data-content-feature="1"><div class="yuRUbf"><span>Han var en av grundarna av Finlands vetenskapsakademi, Finlands kemiska förening (1919) och Åbo universitet (<em>1935</em>). 1917 var han en av grundarna av ...</span><a data-jsarwt="1" data-usg="AOvVaw3NbktYgts6hJJJFTBdDmeN" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFnoECBYQAQ" href="https://books.google.com/books/about/Totalsynthese_der_Santens%C3%A4uren.html?id=4fkRzwEACAAJ"><br /><h3 class="LC20lb MBeuO DKV0Md">Totalsynthese der Santensäuren - Gustaf Komppa - Google Books</h3><div class="TbwUpd NJjxre"><cite class="iUh30 qLRx3b tjvcx" role="text">https://books.google.com<span class="dyjrff qzEoUe" role="text"> › about</span></cite></div></a><div class="B6fmyf"><div class="TbwUpd"><cite class="iUh30 qLRx3b tjvcx" role="text"><span class="dyjrff qzEoUe" role="text"></span></cite></div><div class="eFM0qc"><span class="LAWljd"> · </span><a class="fl iUh30" data-jsarwt="1" data-usg="AOvVaw2ipqCCy1mtVrbhhbHbmB-w" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8Q7gF6BAgWEAU" href="https://translate.google.com/translate?hl=da&sl=en&u=https://books.google.com/books/about/Totalsynthese_der_Santens%25C3%25A4uren.html%3Fid%3D4fkRzwEACAAJ&prev=search&pto=aue"><span>Oversæt denne side</span></a></div></div></div></div><div class="MjjYud"><div data-hveid="CBwQAA"><div class="g"><div><div data-hveid="CBcQAA" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFSgAegQIFxAA" lang="en" style="width: 600px;"><div class="kvH3mc BToiNc UK95Uc" data-sokoban-container="ih6Jnb_Wspraf"><div class="Z26q7c UK95Uc" data-content-feature="1"><div class="VwiC3b yXK7lf MUxGbd yDYNvb lyLwlc lEBKkf" style="-webkit-line-clamp: 2;"><span><em>Gustaf Komppa</em>. Suomalainen Tiedeakatemia, <em>1935</em> - 29 pages. 0 Reviews. Reviews aren't verified, but Google checks for and removes fake content when it's ...</span></div></div></div></div></div><div class="d4rhi"><ul class="FxLDp"><li class="MYVUIe"><div class="XN9cAe"><div data-hveid="CBoQAA" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QtJkDKAB6BAgaEAA" lang="en" style="width: 600px;"><div class="kvH3mc BToiNc UK95Uc" data-sokoban-container="ih6Jnb_pkyjzc"><div class="Z26q7c UK95Uc jGGQ5e" data-header-feature="0"><div class="yuRUbf"><a data-jsarwt="1" data-usg="AOvVaw39bRU29BWRPpg9XgLeu4_R" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFnoECBkQAQ" href="https://books.google.com/books/about/Ueber_die_Darstellung_der_Hexahydro_tere.html?id=RW04SQAACAAJ"><br /><h3 class="LC20lb MBeuO DKV0Md">Ueber die Darstellung der Hexahydro-terephthalsäure - Gustaf ...</h3><div class="TbwUpd NJjxre"><cite class="iUh30 qLRx3b tjvcx" role="text">https://books.google.com<span class="dyjrff qzEoUe" role="text"> › about</span></cite></div></a><div class="B6fmyf"><div class="TbwUpd"><cite class="iUh30 qLRx3b tjvcx" role="text"><span class="dyjrff qzEoUe" role="text"></span></cite></div><div class="eFM0qc"><span class="LAWljd"> · </span><a class="fl iUh30" data-jsarwt="1" data-usg="AOvVaw2CXtpqOXdYCx29alIlw3fM" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8Q7gF6BAgZEAU" href="https://translate.google.com/translate?hl=da&sl=en&u=https://books.google.com/books/about/Ueber_die_Darstellung_der_Hexahydro_tere.html%3Fid%3DRW04SQAACAAJ&prev=search&pto=aue"><span>Oversæt denne side</span></a></div></div></div></div><div class="Z26q7c UK95Uc" data-content-feature="1"><div class="VwiC3b yXK7lf MUxGbd yDYNvb lyLwlc lEBKkf" style="-webkit-line-clamp: 2;"><span>Front Cover. <em>Gustaf Komppa</em>. Suomal. Tiedeakat, <em>1935</em>. 0 Reviews. Reviews aren't verified, but Google checks for and removes fake content when it's identified ...</span></div></div></div></div></div></li></ul></div></div></div></div><div class="MjjYud"><div class="g Ww4FFb vt6azd tF2Cxc" data-hveid="CCAQAA" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFSgAegQIIBAA" lang="sv" style="width: 600px;"><div class="kvH3mc BToiNc UK95Uc" data-sokoban-container="ih6Jnb_ySh00e"><div class="Z26q7c UK95Uc jGGQ5e" data-header-feature="0"><div class="yuRUbf"><a data-jsarwt="1" data-usg="AOvVaw23QO_1Wg67WlAWKarCQIs5" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFnoECB4QAQ" href="https://no-regime.com/ru-sv/wiki/Gustaf_Komppa"><br /><h3 class="LC20lb MBeuO DKV0Md">Gustaf Komppa - Gustaf Komppa - no-regime.com</h3><div class="TbwUpd NJjxre"><cite class="iUh30 qLRx3b tjvcx" role="text">https://no-regime.com<span class="dyjrff qzEoUe" role="text"> › ru-sv › wiki</span></cite></div></a><div class="B6fmyf"><div class="TbwUpd"><cite class="iUh30 qLRx3b tjvcx" role="text"><span class="dyjrff qzEoUe" role="text"></span></cite></div><div class="eFM0qc"><span class="LAWljd"> · </span><a class="fl iUh30" data-jsarwt="1" data-usg="AOvVaw1QVzStzKl4GLmrY3F7Hari" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8Q7gF6BAgeEAU" href="https://translate.google.com/translate?hl=da&sl=sv&u=https://no-regime.com/ru-sv/wiki/Gustaf_Komppa&prev=search&pto=aue"><span>Oversæt denne side</span></a></div></div></div></div><div class="Z26q7c UK95Uc" data-content-feature="1"><div class="VwiC3b yXK7lf MUxGbd yDYNvb lyLwlc lEBKkf" style="-webkit-line-clamp: 2;"><span><em>Gustaf Komppa</em> (28 juli 1867 i Viipuri- 20 januari 1949 i Helsingfors ) var en finsk kemist som ... Från <em>1935</em> till 1945 var han kansler vid Åbo universitet .</span></div></div><div class="Z26q7c UK95Uc"></div></div></div></div><div class="MjjYud"><div class="g Ww4FFb vt6azd tF2Cxc" data-hveid="CCUQAA" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFSgAegQIJRAA" lang="sv" style="width: 600px;"><div class="kvH3mc BToiNc UK95Uc" data-sokoban-container="ih6Jnb_kwO3Rd"><div class="Z26q7c UK95Uc jGGQ5e" data-header-feature="0"><div class="yuRUbf"><a data-jsarwt="1" data-usg="AOvVaw2cJcxXmrM0TzD4nQRXTHVL" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8QFnoECCQQAQ" href="https://www.uppslagsverket.fi/sv/sok/view-170045-KomppaGustaf"><br /><h3 class="LC20lb MBeuO DKV0Md">Komppa, Gustaf - Sök - Uppslagsverket Finland</h3><div class="TbwUpd NJjxre"><cite class="iUh30 qLRx3b tjvcx" role="text">https://www.uppslagsverket.fi<span class="dyjrff qzEoUe" role="text"> › sok</span></cite></div></a><div class="B6fmyf"><div class="TbwUpd"><cite class="iUh30 qLRx3b tjvcx" role="text"><span class="dyjrff qzEoUe" role="text"></span></cite></div><div class="eFM0qc"><span></span></div></div></div></div></div></div></div><div class="Z26q7c UK95Uc jGGQ5e" data-header-feature="0"><div class="yuRUbf"><div class="B6fmyf"><div class="eFM0qc"><a class="fl iUh30" data-jsarwt="1" data-usg="AOvVaw3q1Y6JP0deNq9DTDKfn4Da" data-ved="2ahUKEwj_muWX7Mv6AhVMs4sKHR3OBK8Q7gF6BAgkEAo" href="https://translate.google.com/translate?hl=da&sl=sv&u=https://www.uppslagsverket.fi/sv/sok/view-170045-KomppaGustaf&prev=search&pto=aue"><span>Oversæt denne side</span></a></div></div></div></div><div class="Z26q7c UK95Uc" data-content-feature="1"><div class="VwiC3b yXK7lf MUxGbd yDYNvb lyLwlc lEBKkf" style="-webkit-line-clamp: 2;"><span><em>Komppa</em>
är den mest betydande syntetikern bland Finlands kemister ( kemi). ...
Heidelberg och Uppsala, och var kansler för Turun yliopisto <em>1935</em>-1945. <em>Komppa</em> ...</span></div></div><p> </p>
</li></ul>
<p> </p>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-20949366040994375112022-10-06T13:50:00.002+02:002022-10-06T13:52:07.400+02:00Suomessa tutkittiin kurkumaöljyä vuonna 1921<p>
</p><ul><li><p><a name="multiVolumeLinkVolumes65"></a>Hintikka, Sulo
Viljo [VerfasserIn] <br />
Helsinki: <a href="https://katalog.slub-dresden.de/id/0-118642432X">Zur
Kenntnis des Curcumaöls S. V. Hintikka </a> (Kurkumaöljy)
<br />
Helsinki, Suomalaisen Tiedeakatemian Kustantama, 1921 </p><p> Curcuma longa- sisältää 80% polyfenolisia curcunoideja ja 12% demetoxycurcumiinia. Kurkumaöljyn tuoksuaine on nimeltään turmeron. Curcumaa on curry- mausteessa. Luokituksessa kasvi kuuluu ginger perheeseen Zingiberaceae. </p><p> "Turmeric" katsotaan hyödylliseksi , miellyttäväksi ja terveelliseksi mausteeksi. <br /></p>
</li></ul>
Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-16418809995007902412022-09-21T15:46:00.002+02:002022-09-21T15:49:31.723+02:00Tuoksusumakista maksettiin myös kymmenykset Mishnan mukaan (Maaserot, Peah) <p> PubMed haku Rhus coriaria ,</p><p> Sumach, Bärsumak, Garve-sumak, Parkkisumakki, Tuoksusumakki (Oog HaBurskaaim, Sumak)<br /></p><div class="results-amount">
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<a class="docsum-title" data-article-id="33430013" data-full-article-url="from_term=Rhus+coriaria+&from_pos=1" data-ga-action="1" data-ga-category="result_click" data-ga-label="33430013" href="https://pubmed.ncbi.nlm.nih.gov/33430013/">
Pharmacological and Antioxidant Activities of <i><b>Rhus</b> <b>coriaria</b></i> L. (Sumac).
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<span class="docsum-authors full-authors">Alsamri H, Athamneh K, Pintus G, Eid AH, Iratni R.</span>
<span class="docsum-journal-citation full-journal-citation">Antioxidants (Basel). 2021 Jan 8;10(1):73. doi: 10.3390/antiox10010073.</span>
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<span><b>Rhus</b> <b>coriaria</b> L. (Anacardiaceae),
commonly known as sumac, is a <b>commonly used spice, condiment</b>, and
<b>flavoring agent</b>, especially in the Mediterranean region. ...This plant
is rich in various classes of phytochemicals including flavonoids,
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<a class="docsum-title" data-article-id="32141706" data-full-article-url="from_term=Rhus+coriaria+&from_pos=2" data-ga-action="2" data-ga-category="result_click" data-ga-label="32141706" href="https://pubmed.ncbi.nlm.nih.gov/32141706/">
Phytochemical Diversity and Pharmacological Properties of <b>Rhus</b> <b>coriaria</b>.
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<span class="docsum-authors full-authors">Elagbar ZA, Shakya AK, Barhoumi LM, Al-Jaber HI.</span>
<span class="docsum-journal-citation full-journal-citation">Chem Biodivers. 2020 Apr;17(4):e1900561. doi: 10.1002/cbdv.201900561. Epub 2020 Apr 9.</span>
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<span><b>Rhus</b> <b>coriaria</b> L. (Anacardiaceae),
sumac, is a common condiment,<b> appetizer</b> and <b>souring agent</b> in the
Mediterranean region that has a long history in traditional medicine. R.
<b>coriaria</b> has been prescribed for the <b>treatment of many ailments</b> including diarrhea, ulc</span> …
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The effect of sumac (<b>Rhus</b> <b>coriaria</b> L.) supplementation on glycemic indices: A systematic review and meta-analysis of controlled clinical trials.
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<span class="docsum-authors full-authors">Mohit M, Nouri M, Samadi M, Nouri Y, Heidarzadeh-Esfahani N, Venkatakrishnan K, Jalili C.</span>
<span class="docsum-journal-citation full-journal-citation">Complement Ther Med. 2021 Sep;61:102766. doi: 10.1016/j.ctim.2021.102766. Epub 2021 Aug 5.</span>
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BACKGROUND & AIMS: <b>Rhus</b> <b>coriaria</b> L. (Sumac) is <b>a popular spice/herb</b> with several biological functions owing to its <b>antioxidant and insulin-like activities</b>. ...
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Repressive effect of <b>Rhus</b> <b>coriaria</b> L. fruit extracts on microglial cells-mediated inflammatory and oxidative stress responses.
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<span class="docsum-authors full-authors">Khalil M, Bazzi A, Zeineddine D, Jomaa W, Daher A, Awada R.</span>
<span class="docsum-journal-citation full-journal-citation">J Ethnopharmacol. 2021 Apr 6;269:113748. doi: 10.1016/j.jep.2020.113748. Epub 2020 Dec 24.</span>
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ETHNOPHARMACOLOGICAL RELEVANCE: <b>Rhus</b> <b>coriaria</b>
L. represents a herbal shrub that is used widely in traditional
medicine in the Middle East region to treat different diseases including
<b>inflammation-related disorders.</b> ...However, the effect of R. <b>coriaria</b> on neu …
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<i><b>Rhus</b> <b>coriaria</b></i> L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma.
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<span class="docsum-authors full-authors">Kubatka P, Kello M, Kajo
K, Samec M, Liskova A, Jasek K, Koklesova L, Kuruc T, Adamkov M, Smejkal
K, Svajdlenka E, Solar P, Pec M, Büsselberg D, Sadlonova V, Mojzis J.</span>
<span class="docsum-journal-citation full-journal-citation">Int J Mol Sci. 2020 Dec 26;22(1):183. doi: 10.3390/ijms22010183.</span>
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The aim of this study was to evaluate the oncostatic activities of <b>Rhus</b> <b>coriaria</b> L. (sumac) using animal models (rat and mouse), and cell lines of breast carcinoma. ...In the mouse model, R. <b>coriaria</b> at a higher dose (1%) significantly decreased tumor volume …
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<i><b>Rhus</b> <b>coriaria</b></i> L. (Sumac), a Versatile and Resourceful Food Spice with Cornucopia of Polyphenols.
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<span class="docsum-authors full-authors">Batiha GE, Ogunyemi OM, Shaheen HM, Kutu FR, Olaiya CO, Sabatier JM, De Waard M.</span>
<span class="docsum-journal-citation full-journal-citation">Molecules. 2022 Aug 14;27(16):5179. doi: 10.3390/molecules27165179.</span>
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In recent years, utilization of <b>Rhus</b> <b>coriaria</b>
L. (sumac) is upgrading not only in their<b> culinary</b> use and human
nutrition, but also in the <b>pharmaceutical </b>industry, food industry and
veterinary practices. ...Herein, we discuss polyphenolic compounds as
the main bioact …
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Physiochemical properties and medicinal, nutritional and
industrial applications of Lebanese Sumac (Syrian Sumac - <i><b>Rhus</b> <b>coriaria</b></i>): A review.
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<span class="docsum-authors full-authors">Sakhr K, El Khatib S.</span>
<span class="docsum-journal-citation full-journal-citation">Heliyon. 2020 Jan 27;6(1):e03207. doi: 10.1016/j.heliyon.2020.e03207. eCollection 2020 Jan.</span>
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BACKGROUND: Syrian Sumac, scientifically defined as <b>Rhus</b> <b>coriaria</b>,
is a commonly used spice powder in the Middle East. ...SCOPE AND
APPROACH: Several studies have been done to explore the benefits and
potential uses of <b>Rhus</b> <b>coriaria</b>. In the following r …
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Potential anticancer activities of <b>Rhus</b> <b>coriaria</b> (sumac) extract against human cancer cell lines.
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<span class="docsum-authors full-authors">A Gabr S, H Alghadir A.</span>
<span class="docsum-journal-citation full-journal-citation">Biosci Rep. 2021 May 28;41(5):BSR20204384. doi: 10.1042/BSR20204384.</span>
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The present study aims to evaluate the anticancer activity of sumac (<b>Rhus</b> <b>coriaria</b>)
against different human cancer MCF-7, PC-3, and SKOV3 cell lines. ...In
the present study, the potential antitumor effects of sumac (<b>Rhus</b> <b>coriaria</b>) were explored in the …
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<i><b>Rhus</b> <b>coriaria</b></i> L. Fruit Extract Prevents UV-A-Induced Genotoxicity and Oxidative Injury in Human Microvascular Endothelial Cells.
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<span class="docsum-authors full-authors">Nozza E, Melzi G, Marabini L, Marinovich M, Piazza S, Khalilpour S, Dell'Agli M, Sangiovanni E.</span>
<span class="docsum-journal-citation full-journal-citation">Antioxidants (Basel). 2020 Apr 1;9(4):292. doi: 10.3390/antiox9040292.</span>
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<span><b>Rhus</b> <b>coriaria</b> L. (sumac) is a small
plant widely diffused in the Mediterranean region. ...Our findings
indicate that the extract acts as a<b> cell cycle inhibitor or apoptosis
inducer</b>, according to the level of damage. The present work provides new
insights into the us</span> …
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Sumac (<b>Rhus</b> <b>coriaria</b>) for the prevention and treatment of necrotizing enterocolitis.
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<span class="docsum-authors full-authors">Isik S, Tayman C, Cakir U, Koyuncu I, Taskin Turkmenoglu T, Cakir E.</span>
<span class="docsum-journal-citation full-journal-citation">J Food Biochem. 2019 Dec;43(12):e13068. doi: 10.1111/jfbc.13068. Epub 2019 Oct 3.</span>
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Leukotrienes, free oxygen radicals, tumor necrosis
factor-alpha, and inflammatory mediators play major roles in the
development of necrotizing enterocolitis (NEC). <b>Rhus</b> <b>coriaria</b> (RC: sumac) extracts may enhance cell viability by <b>reinforcing defenses</b> against free rad … </div><div class="full-view-snippet"> </div><div class="full-view-snippet">Tämä sivu on keskeneräinen <br /></div>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-58701117086788444602022-09-21T14:08:00.009+02:002022-09-21T14:22:38.925+02:00Kolokvintin hyviä ja huonoja puolia, liuskamelonilaji, "villikurkuksi" mainittu Raamatussa. Traditionaalinen lääkekasvi monissa kulttuureissa <div class="" dir="auto"><div class="d2hqwtrz r227ecj6 ez8dtbzv gt60zsk1" data-ad-comet-preview="message" data-ad-preview="message" id="jsc_c_8b"><div class="alzwoclg cqf1kptm siwo0mpr gu5uzgus"><div class="jroqu855 nthtkgg5"><span class="gvxzyvdx aeinzg81 t7p7dqev gh25dzvf exr7barw b6ax4al1 gem102v4 ncib64c9 mrvwc6qr sx8pxkcf f597kf1v cpcgwwas m2nijcs8 hxfwr5lz k1z55t6l oog5qr5w tes86rjd pbevjfx6 ztn2w49o" dir="auto"><div class="m8h3af8h l7ghb35v kjdc1dyq kmwttqpk gh25dzvf n3t5jt4f"><div dir="auto" style="text-align: start;">Raamatun kasvi, kolokvintti, eräs liuskamelonilaji on käännetty suom. Raamatussa villikurkkuna. </div><div dir="auto" style="text-align: start;"> Kirjoitin siitä muistiin jotain erääseen blogiini ja siteeraan tähän ystäville: </div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;"> Raamatussa mainittu vihanneskasvi liuskamelonilaji kolokvintti, “villi kurkku”.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;"><span><a tabindex="-1"></a></span>Citrullus colocynthis, Bitter gourds, Awatiah ha-Pakkuah, Kolokvinthus , käännetty sanalla “Villikurkku” suomalaisessa Raamatussa. Entä mitä PubMed kirjoittaa siitä?</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">(Raamatunkohta on ; 2. Kn. 4: 39-40).</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">RAAMATUSSA MAINITAAN tässä kohdassa Elisa-profeetan oppilaiden ruoanlaitosta. Oli nälänhätäaikaa ja oppilasjoukolle täytyi löytää syötävää. Yksi lähti hakemaan jotain vihreää luonnosta ja löysi rönsyilevän kasvin, jossa kasvoi jotain kurkun tapaista hedelmää. Hän poimi sitä viittansa täyteen. Pojat eivät tunnistaneet tätä kasvia. Se leikeltiin pataan ja alettiin syödä soippaa, mutta se ei maistunut kitkeryyden takia. Elisa kuitenkin tiesi neuvon." Villikurkut" olivat kolokvinttejä, joissa on paljon antioksidanttisia ominaisuuksia, mutta myös myrkyllisiä aineksia, joista ällöttävä maku tulee. Ne ainekset sai saostettua jauhoilla myrkyttömiksi ja keitosta tuli syötävää ja maukasta. Opettavainen tarina. Tietämys luonnon antimista on tärkeä, varsinkin kun paikoitellen on nälänhätää maailmassa vieläkin. Kaikki vihreä ei sovi ihmisen ruoaksi. Eläimillä on vaistonsa, ihmisillä vainopittu tietonsa ja taitonsa</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">PubMed lähteestä löytyy tästä kolokvintista artikkeleita ja niitten ohessa lisää viitteitä kolokvintin ainesosien tieteellisestä tutkimuksesta. On havaittu useita vaikuttavia molekyylejä, kukurbitasiineja, flavonoideja, alkaloideja ja fenolihappoja ja niistä on todettu antioksidanttisuutta, antidiabeettisuutta, mikrobien vastaisia vaikutuksia ja syövänvastaisia vaikutuksia , metabolisesti edullisia piirteitä maksan ja suolen toimintaan farmakologissa tutkimuksissa.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Tämä kolokvintti kuuluu niin kiinalaiseen kuin afrikkalaiseen ja Välimeren alueen yrttilääketieteeseen.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Haku Pub Med: Citrullus colocynthis</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">1. Artikkeli vuodelta 2020. Kolokvintin molekyylien farmakologisia vaikutuksia </div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">[Research progress on chemical constituents of Citrullus colocynthis and their pharmacological effects].</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Zheng MS, Liu YS, Yuan T, Liu LY, Li ZY, Huang XL. Zhongguo Zhong Yao Za Zhi. 2020 Feb;45(4):816-824. doi: 10.19540/j.cnki.cjcmm.20191104.201. PMID: 32237481 Review. Chinese.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Citrullus colocynthis is widely distributed in the desert regions of the world. ...As a kind of exterritorialy medicinal material, C. colocynthis has been used in China and introduced successfully. The main active ingredients of C. colocynthis are cucurbitacin, flavonoids, alkaloids and phenolic acids, which have been proven to have antioxidant, anti-diabetic, anti-pathogenic microorganisms and anti-cancer activities in modern pharmacological research. This paper reviews the traditional application, chemical composition and pharmacological effects of C. colocynthis, and provides reference for the in-depth study for the efficacy and mechanism of different components of C. colocynthis. Keywords: Citrullus colocynthis; anti-cancer; anti-diabetes; cucurbitacin.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">2. Aiempi artikkeli vuodelta 2015. Kolokvintin molekyylien rakenteitakin saatavilla siinä artikkelissa.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">2015 Sep 30;20(10):18001-15. Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad Rachid Chawech 1 2 3 , Raoudha Jarraya 4 et al. DOI: 10.3390/molecules201018001 Free PMC article <span><a class="qi72231t nu7423ey n3hqoq4p r86q59rh b3qcqh3k fq87ekyn bdao358l fsf7x5fv rse6dlih s5oniofx m8h3af8h l7ghb35v kjdc1dyq kmwttqpk srn514ro oxkhqvkx rl78xhln nch0832m cr00lzj9 rn8ck1ys s3jn8y49 icdlwmnq cxfqmxzd ezidihy3" href="https://l.facebook.com/l.php?u=https%3A%2F%2Fwww.mdpi.com%2Fmolecules%2Fmolecules-20-18001%2Farticle_deploy%2Fhtml%2Fimages%2Fmolecules-20-18001-g001-550.jpg%3Ffbclid%3DIwAR3EdbwJGB8_aP72sl3CDfaJmbhcjEzHzhdHe8QHaps1LC9r_WHSkfT4E1I&h=AT2Q5f4xYAs5g9JOXmCgM2V6Oj6P0xKWqWQpst0kJi8UiibbZhOw8NFp_Zp-POZRtywVmSXJXy-2DasF5VLn1-g7PbqlK6nNX79FBvlkkZufMnYQ_f4pZjvL_bZp4lf_u4-I&__tn__=-UK-R&c[0]=AT3hVG5v3dlIHxcaJt0yVuQ-J2CtyHtMrugHeL9QajHv6ntsaajwg-WE5huc9nIwaoz_DXYKiyixLXVWowddrhyXmf6k-TMRTciTTpfFSSgZAZGvh0ne0ZXR6NxuIblz0eXH" rel="nofollow noopener" role="link" tabindex="0" target="_blank">https://www.mdpi.com/.../molecules-20-18001-g001-550.jpg</a></span></div><div dir="auto" style="text-align: start;">…</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">3. Vuodelta 2013 on tutkimus kolokvintin siemenextrakteista, jotka ovat antioksidanttisia.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Phytochemical screening and free radical scavenging activity of Citrullus colocynthis seeds extracts.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Benariba N, Djaziri R, Bellakhdar W, Belkacem N, Kadiata M, Malaisse WJ, Sener A. Asian Pac J Trop Biomed. 2013 Jan;3(1):35-40. doi: 10.1016/S2221-1691(13)60020-9. PMID: 23570014 Free PMC article. OBJECTIVE: To study the phytochemical screening of different extracts from Citrullus colocynthis (C. colocynthis ) seeds extracts and to assess their antioxidant activity on the DPPH free radical scavenging. .…</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">4. Artikkeli vuodelta 2018 metabolisista vaikutuksista</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Välimeren alueella kolokvintti mainitaan myös traditionaalisena lääkekasvina ja metabolisesti edullisia vaikutuksia on tutkittu koe-eläimissäkin</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Therapeutic effect of alkaloids and glycosides of colocynth seeds on liver injury, associated with metabolic syndrome in wistar rats, subject to nutritional stress.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Tabani K, Birem Z, Halzoune H, Saiah W, Lahfa F, Koceir EA, Omari N. Pak J Pharm Sci. 2018 Jan;31(1(Suppl.)):277-290. PMID: 29386155</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">The Citrullus colocynthis, commonly called colocynth, is known because of its purgative effects and whose seeds are commonly used as certain diseases treatment, namely liver diseases, in the Mediterranean countries traditional medicine. </div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;"> AIHE:</div><div dir="auto" style="text-align: start;">Aihepiiri: Raamatun kasveista. Villikurkut , Kolokvintti, liuskamelonilaji , Bitter gourd, vild gurkliknande slingerväxt, (Awatiah pakuah), Citrullus colocynthis (II Kuningastenkirja 4: 38-40).</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Ruotsalainen viite: <span><a class="qi72231t nu7423ey n3hqoq4p r86q59rh b3qcqh3k fq87ekyn bdao358l fsf7x5fv rse6dlih s5oniofx m8h3af8h l7ghb35v kjdc1dyq kmwttqpk srn514ro oxkhqvkx rl78xhln nch0832m cr00lzj9 rn8ck1ys s3jn8y49 icdlwmnq cxfqmxzd ezidihy3" href="https://sv.wikipedia.org/wiki/Kolokvint?fbclid=IwAR0nIoPGG8lKu-f9njObVRD056_HfE5cMuSpGuzuSDw3xxdEQX03JH7S3YI" rel="nofollow noopener" role="link" tabindex="0" target="_blank">https://sv.wikipedia.org/wiki/Kolokvint</a></span></div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Suomalainen viite: <span><a class="qi72231t nu7423ey n3hqoq4p r86q59rh b3qcqh3k fq87ekyn bdao358l fsf7x5fv rse6dlih s5oniofx m8h3af8h l7ghb35v kjdc1dyq kmwttqpk srn514ro oxkhqvkx rl78xhln nch0832m cr00lzj9 rn8ck1ys s3jn8y49 icdlwmnq cxfqmxzd ezidihy3" href="https://fi.wikipedia.org/wiki/Kolokvintti?fbclid=IwAR1nVChwgJ6zjsJM5wEcKtgBeAhsMvc3AByelrceycqnZWLg1j0w0hV7Flc" rel="nofollow noopener" role="link" tabindex="0" target="_blank">https://fi.wikipedia.org/wiki/Kolokvintti</a></span></div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Luokitus:</div><div dir="auto" style="text-align: start;">Domeeni:</div><div dir="auto" style="text-align: start;"> Aitotumaiset Eucarya</div><div dir="auto" style="text-align: start;">Kunta:</div><div dir="auto" style="text-align: start;"> Kasvit Plantae</div><div dir="auto" style="text-align: start;">Alakunta:</div><div dir="auto" style="text-align: start;"> Putkilokasvit Tracheobionta</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Kaari:</div><div dir="auto" style="text-align: start;"> Siemenkasvit Spermatophyta</div><div dir="auto" style="text-align: start;">Alakaari:</div><div dir="auto" style="text-align: start;"> Koppisiemeniset Magnoliophytina</div><div dir="auto" style="text-align: start;">Luokka:</div><div dir="auto" style="text-align: start;"> Kaksisirkkaiset Magnoliopsida</div><div dir="auto" style="text-align: start;">Lahko:</div><div dir="auto" style="text-align: start;"> Cucurbitales</div><div dir="auto" style="text-align: start;">Heimo:</div><div dir="auto" style="text-align: start;"> Kurkkukasvit Cucurbitaceae</div><div dir="auto" style="text-align: start;">Suku:</div><div dir="auto" style="text-align: start;"> Liuskamelonit Citrullus</div><div dir="auto" style="text-align: start;">Laji:</div><div dir="auto" style="text-align: start;"> colocynthis</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">Hebrealainen viite: Nissim Krispil:Medicinal plants in Israel and throughout the world. The complete guide. Hed Arzi Publishing House, Or Yehuda 60376. Printed in Israel 2000.Sivut 271.</div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">"Villikurkku" liuskamelonityyppi (citrullus) Kolokvintti (colocynthis) sivulla 29 alareunassa. </div></div><div class="l7ghb35v kjdc1dyq kmwttqpk gh25dzvf jikcssrz n3t5jt4f"><div dir="auto" style="text-align: start;">(Muistiin 21.9.2022. Rannebergissä Ruotsissa. Kirjastonhoitajana toiminut Ofra Nov antanut tämän kirjan minulle vuonna 2002 syntymäpäivälahjaksi).</div></div></span></div></div></div></div>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-8817072095249345752021-12-15T16:24:00.000+01:002021-12-15T16:24:44.830+01:00Curcumin (diferoylmethane)"Indian Saffron", Curcuma longa
<a href="http://en.wikipedia.org/wiki/Turmeric">http://en.wikipedia.org/wiki/Turmeric</a>
<p style="font-style: italic; text-align: justify;"><b>Maustekurkuma</b> (Curcuma longa) on <a href="http://fi.wikipedia.org/wiki/Inkiv%C3%A4%C3%A4ri" title="Inkivääri">inkiväärikasveihin</a> kuuluva <a href="http://fi.wikipedia.org/wiki/Ruohovarsi" title="Ruohovarsi">ruohovartinen</a> kasvi. Sen juurista saatavaa maustetta kutsutaan kurkumaksi. Juuri kuivataan ja jauhetaan, jolloin tuloksena on voimakkaan <a href="http://fi.wikipedia.org/wiki/Keltainen" title="Keltainen">keltainen</a> maustejauhe, jota käytetään usein <a href="http://fi.wikipedia.org/wiki/Curry" title="Curry">currymausteseoksen</a> osana ja muussa eteläaasialaisessa ruoanlaitossa. Kurkumaa käytetään myös keltaisen värin antajana eräissä <a href="http://fi.wikipedia.org/wiki/Sinappi" title="Sinappi">sinapeissa</a> sekä jopa kankaiden värjäykseen.</p><div style="text-align: justify;"><span style="font-style: italic;"> </span></div><p style="font-style: italic; text-align: justify;">Maustekurkumasta uutetaan <a href="http://fi.wikipedia.org/w/index.php?title=Kurkumiini&action=edit&redlink=1" class="new" title="Kurkumiini (sivua ei ole)">kurkumiinia</a>, jota käytetään elintarvikkeissa väriaineena. Kurkumiinin <a href="http://fi.wikipedia.org/wiki/E-koodi" title="E-koodi">E-koodi</a> on E 100.</p><p style="font-style: italic; text-align: justify;">"Intian sahrami ", käytetty myös mausteväärennöksiin sahramin sijasta, kertoo Wikipedia.
</p>
<a href="http://www.ncbi.nlm.nih.gov/pubmed/20924967">http://www.ncbi.nlm.nih.gov/pubmed/20924967</a>
<div class="cit"><a href="http://www.ncbi.nlm.nih.gov/pubmed/20924967#" title="Nutrition and cancer.">Nutr Cancer.</a> 2010;62(7):919-30.<span style="font-weight: bold;"> </span>Curcumin, the golden spice from Indian <span class="highlight" style="background-color:">saffron</span>, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.</div><div class="auths"><a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Goel%20A%22%5BAuthor%5D">Goel A</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22Aggarwal%20BB%22%5BAuthor%5D">Aggarwal BB</a>.</div><div class="aff"><h3 class="label">Source</h3><p>Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas, USA.</p></div><div class="abstr"><h3>Abstract</h3><p>Curcumin (diferuloylmethane), the yellow pigment in Indian <span class="highlight" style="background-color:">saffron</span> (Curcuma longa; also called turmeric, haldi, or haridara in the East and curry powder in the West), has been consumed by people for centuries as a dietary component and for a variety of proinflammatory ailments. Extensive research within the last decade in cell culture and in rodents has revealed that curcumin can sensitize tumors to different chemotherapeutic agents including doxorubicin, 5-FU, paclitaxel, vincristine, melphalan, butyrate, cisplatin, celecoxib, vinorelbine, gemcitabine, oxaliplatin, etoposide, sulfinosine, thalidomide, and bortezomib. Chemosensitization has been observed in cancers of the breast, colon, pancreas, gastric, liver, blood, lung, prostate, bladder, cervix, ovary, head and neck, and brain and in multiple myeloma, leukemia, and lymphoma. Similar studies have also revealed that this agent can sensitize a variety of tumors to gamma radiation including glioma, neuroblastoma, cervical carcinoma, epidermal carcinoma, prostate cancer, and colon cancer. How curcumin acts as a chemosensitizer and radiosensitizer has also been studied extensively. For example, it downregulates various growth regulatory pathways and specific genetic targets including genes for NF-κB, STAT3, COX2, Akt, antiapoptotic proteins, growth factor receptors, and multidrug-resistance proteins. Although it acts as a chemosensitizer and radiosensitizer for tumors in some cases, curcumin has also been shown to protect normal organs such as liver, kidney, oral mucosa, and heart from chemotherapy and radiotherapy-induced toxicity. The protective effects of curcumin appear to be mediated through its ability to induce the activation of NRF2 and induce the expression of antioxidant enzymes (e.g., hemeoxygenase-1, glutathione peroxidase, modulatory subunit of gamma-glutamyl-cysteine ligase, and NAD(P)H:quinone oxidoreductase 1, increase glutathione (a product of the modulatory subunit of gamma-glutamyl-cysteine ligase), directly quench free radicals, and inhibit p300 HAT activity. These preclinical studies are expected to lead to clinical trials to prove the potential of this age-old golden spice for treating cancer patients.</p></div><dl class="rprtid"><dt>PMID:</dt><dd>20924967</dd><dd> [PubMed - indexed for MEDLINE] </dd></dl>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-15971650364122665022020-05-17T01:34:00.000+02:002020-05-17T01:39:14.040+02:00Kiinalaista perinnelääkitystä pandemian aikaan<a href="https://www.ncbi.nlm.nih.gov/pubmed/32308732">https://www.ncbi.nlm.nih.gov/pubmed/32308732</a><br />
<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/32307268">https://www.ncbi.nlm.nih.gov/pubmed/32307268</a><br />
<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/32292697">https://www.ncbi.nlm.nih.gov/pubmed/32292697 </a><br />
Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-778987166688103772020-04-09T15:48:00.000+02:002020-04-09T15:48:39.617+02:00Genisteiinilähteistä ravinnossa <a href="https://www.ncbi.nlm.nih.gov/pubmed/32106575">https://www.ncbi.nlm.nih.gov/pubmed/32106575</a><br />
Soijamaidossa ja muissa soijavalmisteissa Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-56343272387141581632020-03-30T14:43:00.009+02:002022-09-21T14:33:04.072+02:00Katekiinien eduista . Punasolujen osmoottisen resistenssin suojeleminen <a href="https://www.ncbi.nlm.nih.gov/pubmed/32213847">https://www.ncbi.nlm.nih.gov/pubmed/32213847</a><br />
<br />
<div class="cit">
<span role="menubar"><a aria-expanded="false" aria-haspopup="true" href="https://www.ncbi.nlm.nih.gov/pubmed/32213847#" role="menuitem" title="Molecules (Basel, Switzerland).">Molecules.</a></span> 2020 Mar 24;25(6). pii: E1456. doi: 10.3390/molecules25061456.</div>
<h4>
Interaction of Catechins with Human Erythrocytes.</h4>
<div class="auths">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Naparlo%20K%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Naparlo K</a><sup>1</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Bartosz%20G%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Bartosz G</a><sup>2</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Stefaniuk%20I%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Stefaniuk I</a><sup>3</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Cieniek%20B%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Cieniek B</a><sup>3</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Soszynski%20M%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Soszynski M</a><sup>4</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Sadowska-Bartosz%20I%5BAuthor%5D&cauthor=true&cauthor_uid=32213847">Sadowska-Bartosz I</a><sup>1</sup>.<a aria-expanded="false" class="jig-ncbitoggler ui-widget ui-ncbitoggler" href="https://www.ncbi.nlm.nih.gov/pubmed/32213847#" id="ui-ncbitoggler-2" role="button" title="Open/close author information list"><span class="ui-ncbitoggler-master-text"></span></a><br /><a aria-expanded="false" class="jig-ncbitoggler ui-widget ui-ncbitoggler" href="https://www.ncbi.nlm.nih.gov/pubmed/32213847#" id="ui-ncbitoggler-2" role="button" title="Open/close author information list"><span class="ui-ncbitoggler-master-text"></span></a></div>
<div class="afflist">Abstract
</div>
<div class="abstr">
<div>
The
aim of this study was to characterize the interaction of chosen
catechins ((+)-catechin, (-)-epigallocatechin (EGC), and
(-)-epigallocatechin gallate (<span class="highlight">EGCG</span>))
with human erythrocytes and their <b>protective effects against oxidative
damage of erythrocytes. </b>Uptake of the catechins by erythrocytes was
studied by fluorimetry, their interaction with erythrocyte membrane was
probed by changes in erythrocyte osmotic fragility and in membrane
fluidity evaluated with spin labels, while protection against oxidative
damage was assessed by protection against hemolysis induced by
permanganate and <b>protection of erythrocyte membranes against lipid
peroxidation and protein thiol group oxidation.</b> Catechin uptake was
similar for all the compounds studied. Accumulation of catechins in the
erythrocyte membrane was demonstrated by the catechin-induced increase
in osmotic resistance and rigidification of the erythrocyte membrane
detected by spin labels 5-doxyl stearic acid and 16-doxyl stearic acid.
(-)-Epigallocatechin and <span class="highlight">EGCG</span>
inhibited erythrocyte acetylcholinesterase (mixed-type inhibition).
Catechins protected erythrocytes against permanganate-induced hemolysis,
oxidation of erythrocyte protein thiol groups, as well as membrane
lipid peroxidation. These results contribute to the knowledge of the
beneficial effects of catechins present in<b> plant-derived food and
beverages </b>KEYWORDS: </div>
</div>
<div class="keywords">
(−)-epigallocatechin;
(−)-epigallocatechin gallate; antioxidant; catechin; erythrocyte;
hemolysis; membrane rigidity; monometric flavanols</div>
<div class="resc">
<dl class="rprtid"><dt>DOI:</dt>
<dd><a href="https://doi.org/10.3390/molecules25061456" target="_blank">10.3390/molecules25061456</a></dd></dl>
</div>
<span class="status_icon">Free full text</span><span class="status_icon"> Healthline- lähteestä sitaatti: </span><br />
<span class="status_icon">" </span>EGCG is most prevalent in green tea but also found in smaller quantities
in other types of tea, fruit, and some nuts. Other health-promoting
catechins are plentiful in red wine, dark chocolate, legumes, and most
fruit."<br />
<br />
<br />
Muuten, Ruotsin uutisissa puhuttiin tänään elintarviketiloanteen ehkä huononemisesta jopa hedelmien ja vihannesten osalta Euroopassa toimituksista johtuen. Sesonkityöntekijät eivät pääsee liikkumaan pandemiaolosuhteiden takia ja sadonkorjuut jäävät useissa Etelä-Euroopan maissa hoitumatta ehkä, jos ei omista kansalaisista tule sadonkorjuujoukkoja. Ruotsissa saataneen sadonkorjuuväkeä työnvälityksen kautta omastakin maasta. Sinänsä ei tällä hetkellä vaivaa kato-olosuhteet Eurooppaa , kuten Afrikassa heinäsirkkavitsauksen takia. Ainoastaan ihmisten rekrytoiminen sadonkorjuuseen ja valmiin olevaisen ja tulevaisen sadon käsittely ja kuljetus on nyt ongelmatasoa, joka riippuu ihmisestä eikä ilmasta tai eläimistä. Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-46928540278999888322020-03-30T14:07:00.000+02:002020-03-30T14:07:13.236+02:00Epigallokatekiinigallatti ja sen sukuiset funktionaaliset kasvimolekyylit <h4>
<div>
<a href="https://www.blogger.com/null" name="sources"> Naturally found in various foods'</a></div>
<div>
</div>
<div>
<ul>
<li>Epigallokatekiinigallaatti ja sen sukuiset yhdisteet </li>
</ul>
</div>
</h4>
EGCG is probably best known for its role as the major active compound in green tea. <br />
In fact, the numerous health benefits associated with <a class="content-link css-5r4717" href="https://www.healthline.com/nutrition/top-10-evidence-based-health-benefits-of-green-tea">drinking green tea</a> are typically credited to its EGCG content (<a class="content-link css-5r4717" href="https://www.ncbi.nlm.nih.gov/pubmed/24494192" rel="noopener noreferrer" target="_blank">1<span class="css-1mdvjzu icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a><span></span>).<br />
<br />
Though EGCG is predominantly found in green tea, it also exists in small amounts in other foods, such as (<a class="content-link css-5r4717" href="https://www.ars.usda.gov/ARSUserFiles/80400525/Data/Flav/Flav_R03.pdf" rel="noopener noreferrer" target="_blank">3</a>):<br />
<ul>
<li><strong>Tea:</strong> green, white, oolong, and <b>black teas</b></li>
<li><strong>Fruits: cranberries, strawberries, blackberries, kiwis, cherries, pears, peaches, apples, and <a class="content-link css-5r4717" href="https://www.healthline.com/nutrition/12-proven-benefits-of-avocado">avocados</a></strong></li>
<li><strong>Nuts:</strong> pecans, pistachios, and hazelnuts</li>
</ul>
While
EGCG is the most researched and potent catechin, other types like
epicatechin, epigallocatechin, and epicatechin 3-gallate may offer
similar benefits. Plus, many of them are more widely available in the
food supply (<a class="content-link css-5r4717" href="https://www.ars.usda.gov/ARSUserFiles/80400525/Data/Flav/Flav_R03.pdf" rel="noopener noreferrer" target="_blank">3</a>, <a class="content-link css-5r4717" href="https://www.ncbi.nlm.nih.gov/pubmed/26198245" rel="noopener noreferrer" target="_blank">4<span class="css-1mdvjzu icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a><span></span>).<br />
<ul>
<li><h4>
Katekiinit </h4>
</li>
</ul>
Red
wine, dark chocolate, legumes, and most fruit are a few examples of
foods that offer a hefty dose of health-promoting catechins (<a class="content-link css-5r4717" href="https://www.ncbi.nlm.nih.gov/pubmed/10820089" rel="noopener noreferrer" target="_blank">5<span class="css-1mdvjzu icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a><span></span>).Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-43314088277455786582020-03-30T11:42:00.001+02:002020-03-30T11:45:03.832+02:00Ajatuksia koronapandemian aikana .Sulfoirafaani ja kaalikasvit <a href="https://jukuri.luke.fi/handle/10024/470467">https://jukuri.luke.fi/handle/10024/470467</a><br />
<br />
KAALIKASVIT muista<br />
kun asiat ei luista<br />
ja saa aivan pohtia,<br />
mitä syödä tohtia<br />
näinä päivinä pahoina<br />
pandemisina aikoina.<br />
Parsakaali, ruusukaali,<br />
valkokaali, keräkaali,<br />
suippukaali, punakaali,<br />
jokin niistä kotiin haali.<br />
Luomakunnan alusta<br />
dieettiohje Luojalta<br />
koski myöskin kaaleja:<br />
siementä suovaa ruohoa, (Genesis 1:29)<br />
<br />
<br />
CRUCIFERACEDAE tunnetaan nykyisin BRASSICACEAE heimona myös ja siitä saa kasviluetteloja esim lähteestä<br />
<a href="https://www.britannica.com/topic/list-of-plants-in-the-family-Brassicaceae-2004620">https://www.britannica.com/topic/list-of-plants-in-the-family-Brassicaceae-2004620</a><br />
<br />
KAALIT ja sen sukulaiset, BRASSICA<br />
<br />
<ul class="topic-list unordered-list with-dots">
<li><div>
<b>cabbage and relatives (genus <a class="md-crosslink" href="https://www.britannica.com/plant/brassica"><i>Brassica</i>)</a></b><br />
<ul class="topic-list unordered-list with-dots">
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/Chinese-cabbage">bok choy</a> (<i>Brassica rapa</i>, variety <i>chinensis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/mustard">brown mustard</a> (<i>Brassica juncea</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/broccoli">broccoli</a> (<b><i>Brassica oleracea</i></b>, variety <i>italica</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/Brussels-sprouts">Brussels sprouts</a> (<b><i>Brassica oleracea</i>, </b>variety <i>gemmifera</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/cabbage">cabbage</a> (<b><i>Brassica oleracea</i></b>, variety <i>capitata</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/cauliflower">cauliflower</a> (<b><i>Brassica oleracea</i>,</b> variety <i>botrytis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/collard">collard</a> (<b><i>Brassica oleracea</i>,</b> variety <i>acephala</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/kale">kale</a> (<b><i>Brassica oleracea</i>,</b> variety <i>acephala</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/kohlrabi">kohlrabi</a> (<b><i>Brassica oleracea</i>,</b> variety <i>gongylodes</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/celery-cabbage">napa cabbage</a> (<i>Brassica rapa</i>, variety <i>pekinensis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/rape-plant">rape</a> (<i>Brassica napus</i>, variety <i>napus</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/rutabaga">rutabaga</a> (<i>Brassica napus</i>, variety <i>napobrassica</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/turnip">turnip</a> (<i>Brassica rapa</i>, variety <i>rapa</i>)</div>
</li>
</ul>
</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/candytuft">candytuft</a> (genus <i>Iberis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/charlock">charlock</a> (<i><b>Sinapis </b>arvensis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/dames-rocket">dame’s rocket</a> <b>(</b><i><b>Hesperis </b>matronalis</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/honesty">honesty</a> (genus <i>Lunaria</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/horseradish">horseradish</a> (<i>Armoracia rusticana</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/Kerguelen-cabbage">Kerguelen cabbage</a> (<i>Pringlea antiscorbutica</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/pennycress">pennycress</a> (genus <i>Thlaspi</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/peppergrass">peppergrass</a> (genus <i>Lepidium</i>)</div>
</li>
<li><div>
<a class="md-crosslink" href="https://www.britannica.com/plant/radish">radish</a> (<i><b>Raphanus </b>sativus</i>)</div>
</li>
</ul>
<br />Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-10948394054799630002019-09-02T13:04:00.002+02:002019-09-06T23:03:29.350+02:00Fineli.fi tieto pihlajanmarjasta(Sorbus aucuparia, vanlig rönn) <span class="segment segment-3">
<a aria-controls="f-457" aria-expanded="false" class="collapsed" data-parent="#accordion" data-toggle="collapse" href="https://fineli.fi/fineli/fi/elintarvikkeet?q=pihlajanmarja&foodType=ANY#f-457" role="button">
<span class="sr-only">Pihlajanmarjasta marmelaatia: </span></a></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj0ymi3_wf4cpxJjjPpTVy5-W9YXSQ1wklqfmAMsZ2tCOwjarU6T2u60uCFB3AHN9QxqAmKHZ1lP3UVgNYYe4WuU7IHXfvnxMa5k2lS-y1W2yWeKTapVA4azffLWVsT8nwghau0O-KkO7Qg/s1600/Pihlajanmarjamarmelaatia+2019.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1000" data-original-width="1600" height="200" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj0ymi3_wf4cpxJjjPpTVy5-W9YXSQ1wklqfmAMsZ2tCOwjarU6T2u60uCFB3AHN9QxqAmKHZ1lP3UVgNYYe4WuU7IHXfvnxMa5k2lS-y1W2yWeKTapVA4azffLWVsT8nwghau0O-KkO7Qg/s320/Pihlajanmarjamarmelaatia+2019.jpg" width="320" /></a></div>
<span class="segment segment-3"><span class="sr-only">6.9. 2019. keräsin pussillisen pihlajanmarjoja ja noin 10 ruusunmarjaa. Osan pihlajanmarjoista pakastin pieneen rasiaan talven varalta. os oli heitettävä pois, koska niissäoli jonkin pistiäisen tekemää laikkua ja jälkeä. loput aloin keittää vähässä vesitilkassa marmelaatiksi. Noin 8 ruusunmrjaa halkasin, poistin siemenet ja asetin kuoret myös pihlajanmarjoen joukkoon. kun marjat ja vesi kiehuivat , lisäsin sokeria saman tilavuuden verran kuin marjoja oli pienessä kattilassa. Siten keitin seosta ja hämmensin 15 minuutin ajan. Se alkoi muuntua marmelaadiseksi. Siten pesin pienen lasipurkin , jossa oli tähteet maapähkinästä. Asetin marmelaadin siihen ja purkki tuli puolilleen,. Se on herkullisen hyvää ja väkevää. , sopivan sokerista, ettei tunnu liian happamelta. </span></span><br />
<br />
<span class="segment segment-3"><span class="sr-only"> Nyt illalla teemme vohveleita. Päälle voi asetata kermavaahtoaja nokareen pihlajanmarjahilloa. </span></span><br />
<span class="segment segment-3"><span class="sr-only">Muuten , vaikka keräsin marjoja terttuineen ja lehtineen kahden litran pussiin vain puolilleen, siinä tuli luonnon itikoita aika monta ja niitä sai karistaa ulos. muutamia tvestrjärtin tapainen kiemurtelevä metallisen värinen itikka, pari kolme erikokoista hämähäkkiä ja lukkia. joitan lehdenvihreitä isohkoja itikoita myös. Siis aika iso fauna pienessä määrässä flooraa. </span></span><br />
<br />
<span class="segment segment-3"><span class="sr-only">Saattoi itikka olla olla pshlajanmarjapistiäinen, joka oli pistänyt niin monta marjaa. sama joka tekee omenapuihin sitä muumitautia. Sen nimi Argyresthia conjugella . Katson mitä wiki vikisee. </span></span><br />
<span class="segment segment-3"><span class="sr-only"><br /></span></span>
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<span class="segment segment-3"><span class="sr-only">Pihlajanmarja</span>
</span>
<span class="segment segment-1">
</span><br />
<h2>
<a href="https://fineli.fi/fineli/fi/elintarvikkeet/457?q=pihlajanmarja&foodType=ANY&portionUnit=G&portionSize=100&sortByColumn=name&sortOrder=asc&component=2331&">Pihlajanmarja</a>
</h2>
<div class="btn-group quick-select">
</div>
<span class="segment segment-1">
</span><span class="segment segment-1">
</span><br />
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<span class="segment segment-2">
313 kJ
(75 kcal)
</span>
</div>
</div>
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<a aria-controls="f-35597" aria-expanded="false" class="collapsed" data-parent="#accordion" data-toggle="collapse" href="https://fineli.fi/fineli/fi/elintarvikkeet?q=pihlajanmarja&foodType=ANY#f-35597" role="button">
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<span class="sr-only">Pihlajanmarja, kuivattu, pihlajanmarjajauhe</span>
</a>
</span>
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</span><br />
<h2>
<span class="segment segment-1">
<a href="https://fineli.fi/fineli/fi/elintarvikkeet/35597?q=pihlajanmarja&foodType=ANY&portionUnit=G&portionSize=100&sortByColumn=name&sortOrder=asc&component=2331&">Pihlajanmarja, kuivattu, pihlajanmarjajauhe</a>
</span></h2>
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<div class="panel-heading">
<span class="segment segment-2">
1 103 kJ
(263 kcal)
</span>
</div>
</div>
<div class="panel panel-fineli">
<div class="panel-heading">
<span class="segment segment-3">
<a aria-controls="f-35598" aria-expanded="false" class="collapsed" data-parent="#accordion" data-toggle="collapse" href="https://fineli.fi/fineli/fi/elintarvikkeet?q=pihlajanmarja&foodType=ANY#f-35598" role="button">
<span class="fa collapse"></span>
<span class="sr-only">Täysmehu, pihlajanmarjatäysmehu</span>
</a>
</span>
<span class="segment segment-1">
</span><br />
<h2>
<span class="segment segment-1">
<a href="https://fineli.fi/fineli/fi/elintarvikkeet/35598?q=pihlajanmarja&foodType=ANY&portionUnit=G&portionSize=100&sortByColumn=name&sortOrder=asc&component=2331&">Täysmehu, pihlajanmarjatäysmehu</a>
</span></h2>
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121 kJ
(29 kcal) </span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjX4QfnqzawGs5EWdCGcmgW24oyue6EuGYGC5U2e0TYEUbAaLzrtk5_Aw_ymrw0ofPCPrqf7yBGs8dqOWbUgjlXZ_WDjCn70zBbddxNzd2qG4hwbRXnwAa9nMZETILeRT-OnMUulR4fkzoe/s1600/2019-08-13.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1533" data-original-width="1023" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjX4QfnqzawGs5EWdCGcmgW24oyue6EuGYGC5U2e0TYEUbAaLzrtk5_Aw_ymrw0ofPCPrqf7yBGs8dqOWbUgjlXZ_WDjCn70zBbddxNzd2qG4hwbRXnwAa9nMZETILeRT-OnMUulR4fkzoe/s320/2019-08-13.jpg" width="213" /></a></div>
<span class="segment segment-2"> Tällainen pirteä nuori pihlaja on kaikessa hiljaisuudessa kasvanut Sahalinintatar-alueellani ja nyt tänä vuonna kun oli aika leikata tatarkasvu, pääsi näin monimarjainen pihlajakin ensiesiintymäänsä marjalastissaan. </span><br />
<span class="segment segment-2"> </span>
</div>
</div>
</div>
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Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com1tag:blogger.com,1999:blog-5053133206211396187.post-79096966860795422882019-09-02T13:02:00.000+02:002019-09-02T13:11:35.107+02:00Pihlajanmarjasta (S. aucuparia) tieteellistä tietoa <div class="sensor_head">
<div class="portlet_title">
<h3>
Ensinnäkin nimestä</h3>
<ol>
<li><h3>
<span style="font-weight: normal;"><b> Tavallinen pihlaja</b>, Sorbus aucuparia, vanlig rönn. </span></h3>
</li>
<li><h3>
<span style="font-weight: normal;"> Sorbus aria, <b>Saksanpihlaja</b>, jättevitoxel </span></h3>
</li>
<li><h3>
<span style="font-weight: normal;">Sorbus intermedia, S. suecica , <b>Ruotsinpihlaja,</b> oxel </span><b> </b></h3>
</li>
</ol>
<h3>
<span style="font-weight: normal;">Ruotsinpihlaja (<i>Sorbus intermedia</i>) on Etelä-<a href="https://fi.wikipedia.org/wiki/Ruotsi" title="Ruotsi">Ruotsissa</a> ja lounaisimmassa <a href="https://fi.wikipedia.org/wiki/Suomi" title="Suomi">Suomessa</a> kasvava, muuallakin puistopuuna yleinen pihlajalaji. Alkujaan <a href="https://fi.wikipedia.org/wiki/Carl_von_Linn%C3%A9" title="Carl von Linné">Linné</a> antoi sille tieteellisen nimen <i>S. suecica</i>. Ruotsinpihlaja on saanut alkunsa <a href="https://fi.wikipedia.org/wiki/Kotipihlaja" title="Kotipihlaja">kotipihlajan</a>, <a href="https://fi.wikipedia.org/wiki/Etel%C3%A4npihlaja" title="Etelänpihlaja">etelänpihlajan</a> ja <a href="https://fi.wikipedia.org/wiki/Saksanpihlaja" title="Saksanpihlaja">saksanpihlajan</a><sup class="reference" id="cite_ref-2"><a href="https://fi.wikipedia.org/wiki/Ruotsinpihlaja#cite_note-2">[2]</a></sup> tai jonkin sen läheisen sukulaislajin risteymänä.</span></h3>
<h3>
</h3>
<h3>
Best matches for <b>Sorbus</b> <b>aucuparia</b>:</h3>
</div>
</div>
<div lang="en">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/28845915"><b>Sorbus</b> <b>aucuparia</b> and <b>Sorbus</b> aria as a Source of Antioxidant Phenolics, Tocopherols, and Pigments.</a>
<span class="details">Šavikin KP et al. Chem Biodivers.
(2017)</span><br />
<span class="details"> </span>Abstract<br />
<div class="abstr">
<div class="">
Due to its nutritive and medicinal properties, berries of some <span class="highlight">Sorbus</span>
species are used for the preparation of <b>jams </b>and <b>jelly </b>as well as in <b>
traditional medicine</b>. On the other hand, their chemical composition is
not much studied especially of those grown in Balkan Peninsula. We have
analyzed individual <b>phenolics</b>, <b>tocopherols</b>, <b>carotenoids</b> and <b>chlorophylls</b>
using HPLC in <b>berries </b>from <b><span class="highlight">Sorbus</span> <span class="highlight">aucuparia</span></b> and <b><span class="highlight">Sorbus</span>
aria</b> collected in different localities in Serbia and Montenegro
together with the amounts of <b>total phenolics and proanthocyanidins </b>as
well as their <b>radical scavenging activity </b>against DPPH radical.<br />
Berries
of S. <span class="highlight">aucuparia</span>
were richer source of polyphenolics in comparision with S. aria and,
regardless the species and locality, <b>caffeoylquinic acid</b>s such as
neochlorogenic and chlorogenic acid were the most abundant compounds.<br />
Among analyzed tocopherols the most abundant in all samples was
<b>α-tocopherol </b>(0.48 - 19.85 μg/g dw) as it was <b>β-carotene</b> among
carotenoids (mean concentration of 0.98 μg/g dw in S. <span class="highlight">aucuparia</span>
and 0.40 μg/g dw in S. aria, respectively). Correlation between total
phenolics and DPPH radical scavenging activity was noticed. Our study
represents comprehensive report on chemical composition of S. <span class="highlight">aucuparia</span> and S. aria which could contribute to a better understanding of their quality.<br />
<div class="copyright">
© 2017 Wiley-VHCA AG, Zurich, Switzerland. KEYWORDS: </div>
</div>
</div>
<div class="keywords">
<span class="highlight">Sorbus</span>
; Antioxidant; Phenolics; Pigments; Tocopherols</div>
<br />
<span class="details"> </span>
</div>
<div lang="en">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/30630328">Research in the chemical composition of the bark of <b>Sorbus</b> <b>aucuparia</b>.</a>
<span class="details">Krivoruchko E et al. Ceska Slov Farm.
(Wint)</span>Abstract<br />
<div class="abstr">
<div class="">
The quantitative
contents of 40 carboxylic acids, with the prevalence of hexadecanedioic,
lignocerinic, behenic, azelaic, palmitic and benzoic acids, and 39
components of essential oil were determined in the extracts of the bark
of <span class="highlight">Sorbus</span> <span class="highlight">aucuparia</span>
by the GC-MS method. The quantitative contents of 6 phenolic compounds,
i.e., chlorogenic, caffeic, and gallic acids, catechin, quercetin, and
apigenin-7-glucoside were determined by the HPLC method in the ethanolic
extract of the bark of <span class="highlight">Sorbus</span> <span class="highlight">aucuparia</span>. Key words: <span class="highlight">Sorbus</span> <span class="highlight">aucuparia</span> bark, carboxylic acids, phenolic compounds, essential oil, GC-MS, HPLC.</div>
</div>
<div class="keywords">
<br /></div>
<span class="details"> </span>
</div>
<div lang="en">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/27878717">Antitumor Effects of <b>Sorbus</b> <b>aucuparia</b> L. Extract Highly Saturated with Anthocyans and Their Mechanisms.</a>
<span class="details">Razina TG et al. Bull Exp Biol Med.
(2016)</span> Abstract<br />
<div class="">
The effects of
<b>Fructus Sorbi aucupariae extract</b>, originally saturated with anthocyans,
on the development of Lewis lung carcinoma and B-16 melanoma in C57Bl/6
mice and the efficiency of cyclophosphamide treatment were studied.
Antitumor activity of the extract and potentiation of the antimetastatic
activity of the cytostatic were demonstrated. Studies on melanoma B-16
model revealed an increase in the counts of stromal progenitor cells in
the tumor node and their accelerated maturation after treatment with the
extract. No effects towards the tumor stem and committed cells were
detected.KEYWORDS:B-16 melanoma; Fructus Sorbi aucupariae; Lewis lung carcinoma; anthocyans; tumor stem cells PMID: 27878717 DOI:<a href="https://doi.org/10.1007/s10517-016-3554-4" target="_blank"> 10.1007/s10517-016-3554-4</a></div>
</div>
<div lang="en">
<br /></div>
<div lang="en">
<span class="details"> </span>
</div>
Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-64723955800307077142019-09-02T12:28:00.001+02:002019-09-02T13:11:08.574+02:00Pihlajanmarja , Sorbus aucuparia (vanlig rönn)Löytämiäni linkkejä pihlajanmarjan käytöstä:<br />
Otan allaolevan sitaatin muistiin, ksoka oli kerran aika, jolloin ekonomian takia oli vaikea saada kokoon ravitsevia C- vitamiini ja antioksidanttipitoisia hilloaineksia talvea varten. Silloin keräsin mm pihlajanmarjoja. Niitä näkyy t'n'ävuonnakin olevan runsaasti. sen sijaan mustikoista on kato ja vattuja on vain vähän. <br />
<br />
<a href="https://fi.newsner.com/uutiset/syo-vain-3-pihlajanmarjaa-paivassa-ja-nama-muutokset-tapahtuvat-kehossasi/">https://fi.newsner.com/uutiset/syo-vain-3-pihlajanmarjaa-paivassa-ja-nama-muutokset-tapahtuvat-kehossasi/</a><br />
<br />
"Voit lukea alapuolelta viisi syytä, miksi sinun tulisi poimia ja syödä syksyn aikana pihlajanmarjoja.<br />
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<b>Vastustuskykysi vahvistuu </b><br />
Pihlajanmarja on luonnollinen vitamiinipommi, joka vahvistaa kehosi vastustuskykyä. Marjoja käytettiin aikaisemmin jopa rohtona erilaisten sairauksien hoitamiseen.<br />
Pihlajanmarjat auttavat ..
virtsaputkentulehdukseen, sekä hoitamaan flunssaa. Myös karpaloilla ja
puolukoilla on samankaltaisia terveydellisiä ominaisuuksia.<br />
Sinun ei tarvitse syödä paljoa, jotta saat terveydelliset hyödyt
talteen. Fakta on, että sinun tulee syödä vain kolme pihlajanmarjaa
päivässä, jotta saat täytettyä kehosi päivittäisen C-vitamiiniannoksen.<br />
<b>Lievittää särkyä</b><br />
Pihlajanmarjat sisältävät antioksidantteja, rautaa ja karoteenia. Kyseessä on todellinen terveyspommi, joka voi ehkäistä jopa reumaa. "<br />
<br />
<b>Hyväksi vatsallesi</b><br />
Onko sinulla kova vatsa tai ummetusta? Pihlajanmarjat saattavat
auttaa, koska ne sisältävät sorbitolia, jolla on lievästi laksatiivinen
vaikutus. Nauti muutama marja, lähde kävelylle ja vatsasi saattaa toimia
tämän jälkeen paremmin!<br />
<b>Ne ovat herkullisia! </b><br />
Pihlajanmarjat eivät välttämättä maistu sellaisenaan herkulliselta,
mutta ne sopivat hyvin marmeladeihin ja hilloihin. Tuolloin ne maistuvat
huomattavasti paremmalta. Niitä voi myös lisätä leivän tai myslin
sekaan.<br />
Marjoja voi kerätä pakkasyön jälkeen, jolloin ne ovat makeampia. Voit
laittaa niitä myös pakastimeen, jolloin saat saman efektin aikaiseksi.<br />
<b>Säilöntäaineita ei tarvita</b><br />
Pihlajanmarjat sisältävät luonnostaan paljon bentsoehappoa, jonka
vuoksi et tarvitse säilöntäaineita, kun valmistat hilloa, marmeladia tai
hyytelöä.<br />
<b>Pihlajanmarjat ovat</b> <b>terveellisiä</b>,
mutta niitä tulee kuitenkin syödä maltillisesti. Tarvitset vain 3-4
marjaa päivässä, jotta saat kaikki terveydelliset hyödyt irti. Voit
poimia suuren määrän pihlajanmarjoja syksyllä ja säilöä ne pakastimeen,
jotta saat nauttia marjoja ympäri vuoden. <a href="http://forum.odla.nu/index.php?showtopic=77524" rel="nofollow" target="_blank">Useat ihmiset</a> kertovat, että tämä menetelmä pitää flunssan tehokkaasti loitolla.<br />
<i>Muista, että pihlajanmarjat eivät kuulu jokamiehenoikeuksiin,
joten kysy lupaa maanomistajalta tai poimi niitä omalta pihaltasi. </i><br />
Minä en tiennyt, että pihlajanmarjat sisältävät näin valtavia
määriä vitamiineja — erityisesti C-vitamiinin määrä teki vaikutuksen!<br />
Jaa tämä artikkeli Facebookissa — Suomi on täynnä pihlajanmarjoja, jotka voivat ehkäistä flunssaa ja muita sairauksia. <b>"</b>( Kirjoittaja on henkilö, joka on Newsner Finlandian toimitaja)<b> </b><br />
<br />
<br />
<br />Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-38265126037494929122019-05-22T11:00:00.004+02:002019-05-22T11:00:57.076+02:00CURCUMA <a href="https://www.ncbi.nlm.nih.gov/pubmed/30849507">https://www.ncbi.nlm.nih.gov/pubmed/30849507</a>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-15019519571380449052019-03-22T19:56:00.004+01:002019-03-22T19:56:50.016+01:00Suoliston funktionaalisista häiriöistä uusien artikkelien sarja<a href="https://www.ncbi.nlm.nih.gov/pubmed/30879252">https://www.ncbi.nlm.nih.gov/pubmed/30879252</a><br />
<div class="results_settings one_setting" id="result_action_bar">
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<li><a aria-expanded="false" aria-haspopup="true" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" href="https://www.ncbi.nlm.nih.gov/pubmed/30879252#" id="Display" name="Display" role="button"><span class="label">Format</span><span class="separator">: </span><span class="value">Abstract</span><span class="tgt_dark" href="https://www.ncbi.nlm.nih.gov/pubmed/30879252#"></span></a></li>
</ul>
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<div class="cit">
<span role="menubar"><a aria-expanded="false" aria-haspopup="true" href="https://www.ncbi.nlm.nih.gov/pubmed/30879252#" role="menuitem" title="Advances in therapy.">Adv </a></span></div>
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<span role="menubar"><a aria-expanded="false" aria-haspopup="true" href="https://www.ncbi.nlm.nih.gov/pubmed/30879252#" role="menuitem" title="Advances in therapy.">Ther</a></span><br />
<div class="cit">
2019 Mar 16. doi: 10.1007/s12325-019-00924-7. [Epub ahead of print]</div>
<h4>
Bloating and Abdominal Distension: Clinical Approach and Management.<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Mari%20A%5BAuthor%5D&cauthor=true&cauthor_uid=30879252"> Mari A</a><sup>1,</sup><sup>2,</sup><sup>3</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Abu%20Backer%20F%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Abu Backer F</a><sup>1</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Mahamid%20M%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Mahamid M</a><sup>2,</sup><sup>3</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Amara%20H%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Amara H</a><sup>2</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Carter%20D%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Carter D</a><sup>4,</sup><sup>5</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Boltin%20D%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Boltin D</a><sup>6,</sup><sup>5</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Dickman%20R%5BAuthor%5D&cauthor=true&cauthor_uid=30879252">Dickman R</a><sup>7,</sup><sup>8</sup>.</h4>
<div class="abstr">
<h3>
TIIVISTELMÄ, Abstract</h3>
<div class="">
Funktionaaliset mahanpömpötykset ja suolen ( kivuliaat) venyttymät ilmavaivoista (FABD) ovat tavallisia gastrointestinaalisia vaivoja ja niitä gastroenterologit ja terveydenhoitoa tarjoavat kohtaavat päivittäin. Funktionaalinen vatsanpömpötys on subjektiivinen olotila, johon tavallisti liittyy objektiivisesti havaittava suolien laajentuma. FABD voidaan diagnostisoida omana kokonaisuutenaan tai päävaivana tai se voi kattaa muitakin funktionaalisia mahasuolihäiriöitä kuten toiminnallista ummetusta, ärtyneen suolen oireyhtymää (IBS) tai toiminnallista dyspepsiaa. FABD:n patogysiologiaa ei täysin ymmärretä. On ehdotettu taustalla oleviksi mekanismeiksi viskeraalista ( sisäelinten) yliherkkyyttä, käytöksellisesti indusoitunutta epänormaalia vatsaseinämä- palleahermon- refleksejä, huonosti imeytyvien sulavien hiilihydraattien vaikutusta ja mikrobiomin muuntumisia. Hoitoon kuuluu behavioristinen terpaia elämäntapaohjeet), dieetti-interventiot, mikrobiomin modulaatio ja lääketerapia. Tässä katsauksessa esitetään nykytietoa FABD:n patofysiologiasta, arvioinnista ja hoidosta. <br />
<br />
<ul>
<li>Functional abdominal bloating and distension (FABD) are common <span class="highlight">gastrointestinal</span>
complaints, encountered on a daily basis by gastroenterologists and
healthcare providers. Functional abdominal bloating is a subjective
sensation that is commonly associated with an objective abdominal
distension. FABD may be diagnosed as a single entity (the sole or
cardinal complaint) or may overlap with other functional <span class="highlight">gastrointestinal</span>
disorders such as functional constipation, irritable bowel syndrome,
and functional dyspepsia. The pathophysiology of FABD is not completely
understood. Proposed underlying mechanisms include visceral
hypersensitivity, behavioral induced abnormal abdominal wall-phrenic
reflexes, the effect of poorly absorbed fermentable carbohydrates, and <span class="highlight">microbiome</span> alterations. Management includes behavioral therapy, dietary interventions, <span class="highlight">microbiome</span>
modulation, and medical therapy. This review presents the current
knowledge on the pathophysiology, evaluation, and management of FABD.</li>
</ul>
</div>
</div>
<div class="keywords">
<h4>
KEYWORDS: </h4>
Distension; Suolen ( kivulias) venyminen, laajeneminen, , mikä tunnetaan koliikkina, kipuna. <br />
Functional abdominal bloating; Toiminnallinen mahanpömpötys <br />
Functional constipation, toiminnallinen ummetus; <br />
Functional dyspepsia;toiminnallinen happovaiva, ruoansulatusvaiva <br />
Irritable bowel syndrome, ärtyneen suolen oireyhtymä IBS.</div>
<div class="aux">
<div class="resc">
<dl class="rprtid">
<dt>PMID:</dt>
<dd>30879252</dd>
<dt>DOI:</dt>
<dd><a href="https://doi.org/10.1007/s12325-019-00924-7" target="_blank">10.1007/s12325-019-00924-7</a></dd><dd></dd><dd></dd><dd></dd></dl>
<h2 class="Heading">
Määritelmä , Definition</h2>
Vuonna Rooma-IV- työtiimi uudisti Rooma-III- diagnostiset kriteerit ja päivitti kliinisen arvion ja hoidon tähän funktionaaliseen mahanpömpötykseen ja koliikkeja aiheuttavaan suolen epänormaaliin laajentumiseen. Rooma-IV:n mukaan FABD:tä luonnehtii toistuvasti ilmenevät subjektiiviset mahantäyteyden ja paineen oireet tai tunne mahaan jäävän kaasun aiheuttamasta pömpötyksestä ja suolten laajenemisesta ja objektiivisesti mitattavissa oleva lisääntyminen mahan ympärysmitassa. Pömpötys ja mahan ympärysmitan laajeneminen saattavat olla orgaanisten häiriöiden ilmenemismuotoja ja ne pitäisi diagnosoida ja hoitaa erikseen. Tässä annetaan luettelo tavallisista ei-funktionaalisista etiologioista: </div>
<div class="resc">
keliakia,</div>
<div class="resc">
haimantoimninnan vajaus,</div>
<div class="resc">
mahalaukun lihasten hermojen toiminnan heikkous eli gastropareesi, </div>
<div class="resc">
diabetes mellitus</div>
<div class="resc">
kilpirauhasen alitoiminta,</div>
<div class="resc">
skleroderma ( eräs sidekudostauti) </div>
<div class="resc">
suoliston krooninen idiopaattinen pseudotukos,</div>
<div class="resc">
ohutsuolen bakteeriston ylikasvu,</div>
<div class="resc">
akuutti mahalaukun ja suolen tulehdus, </div>
<div class="resc">
mahalaukun pahanlaatuinen tauti, </div>
<div class="resc">
suoliston pahanlaatuinen tauti,</div>
<div class="resc">
munasarjojen pahanlaatuinen tauti, nestettä vatsaontelossa. </div>
<div class="resc">
<br /></div>
<div class="resc">
<ul>
<li>In
2016, the Rome IV working team revised the Rome III diagnostic criteria
and updated the clinical evaluation and treatment for functional
abdominal bloating and distension (FABD) [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR1" role="button" title="View reference">1</a></span>].
According to the Rome IV, FABD is characterized by (subjective)
symptoms of recurrent abdominal fullness, pressure, or a sensation of
trapped gas (bloating), and/or measurable (objective) increase in
abdominal girth (distention) [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR1" role="button" title="View reference">1</a></span>].
Bloating and distension may be the manifestations of organic <b>disorders </b>
which should be diagnosed and treated separately. Common non-functional
etiologies are listed in (Table <span class="InternalRef"><a href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#Tab1">1</a></span>).</li>
</ul>
</div>
<ol>
<li>Non- functional ethiologies. </li>
<li>Celiac disease</li>
<li>Lactose, fructose, and other carbohydrates intolerance</li>
<li>Pancreatic insufficience</li>
<li>Gastroparesis</li>
<li>Diabetes mellitus</li>
<li>Hypothyreoidosis</li>
<li>Scleroderma</li>
<li>Chronic idiopathic pseudo-obstruction</li>
<li>Small intestinal bacterial overgrowth(SIBO)</li>
<li>Acute gastroenteritis</li>
<li>gastric malignancy </li>
<li>Bowel malignancy</li>
<li>Ovarian malignancyAscites </li>
</ol>
<div class="resc">
<br />
Primääri FABD pitäisi diagnosoida omana kokonaisuutenaan (joko yksittäisenä oireena tai pääoireena), joka ei kata toisten toiminnallisten mahasuolihäiriöiden (FGID) aluetta kuten funktionaalista ummetusta (FC), ärtyneen suolen oireyhtymää (IBS) ja toiminnallista ruoansulatushäiriötä (FD). Rooma-IV- diagnostiset kriteerit sallivat lievän mahanaluekivun ja/tai vähäisiä suolistoliikkeiden poikkeavuuksia tähän diagnoosiin. Lopuksi mainittakoon, että oireilun alusta pitäisi olla kulunut aikaa vähintäin 6 kuukautta ja vallitsevia oireita (pömpötystä ja suolten laajenemista) pitäisi olla esiintynyt viimeksi kuluneet 3 kuukautta.<br />
<br />
<ul>
<li>Primary FABD should be diagnosed as a single entity (the sole or
cardinal complaint) that does not overlap with other functional
gastrointestinal disorders (FGID) such as functional constipation (FC),
irritable bowel syndrome (IBS), and functional dyspepsia (FD). However,
Rome IV diagnostic criteria permit the coexistence of mild abdominal
pain and/or minor bowel movement abnormalities. Finally, symptom onset
should be at least 6 months before diagnosis and the predominant symptom
(bloating or distention) should be present during the last 3 months [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR1" role="button" title="View reference">1</a></span>]. </li>
</ul>
<a href="https://www.blogger.com/goog_293648983"><br /></a>
<a href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#Fig1">https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#Fig1</a><br />
<br />
<h3>
Epidemiologia, Epidemiology </h3>
Mahan paisumista, pömpötystä on raportoitu 30% lla aikuisväestöstä ja IBS- potilailla sitä on melkein jokaisella. Kuitenkin vain noin puolella mahan pömpötystä kärsivistä raportoidaan mahan objektiivista laajentumista. Lisäksi mahanpömpötys on tavallisempaa IBS- potilailla ja mahan laajeneminen tavallisempaa kroonisessa ummetuksessa. Puhelinhaastttelussa todettiin USA.ssa 165:lla aikuisista viimeksi kuluneen kuukauden aikana olleen mahan paisumista ja suolten laajenemista. Naiset miehiä useammin raportoivat mahan pömpötykssetä ( 19% , ja vastaavasti 10.5 %) ja naisilla oli myös useammin vakavia oireita ( 24% ja 13 %) . Muissa tutkimuksissa ei ole havaittu eri prevalensseja mahanpömpötyksessä naisilla ja miehillä ( 21% ja 19%) <br />
<ul>
<li>Bloating and distension have been reported by 30% of the adult general
population and are almost universal among patients with IBS [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR2" role="button" title="View reference">2</a></span>].
However only about half of the patients with bloating also report
abdominal distension. In addition, bloating is more common among
patients with IBS, and distension is more common in patients with
chronic constipation [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR3" role="button" title="View reference">3</a></span>].
A telephone survey reported a prevalence of 16% in US adults who were
asked about bloating or distension during the last month [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR4" role="button" title="View reference">4</a></span>].
Women were more likely than men to report bloating (19% vs 10.5%) and
were more likely to have severe symptoms (24% vs 13%). However, other
studies have not identified different prevalence rates of bloating by
gender (21% and 19%) [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR3" role="button" title="View reference">3</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR5" role="button" title="View reference">5</a></span>]. </li>
</ul>
<h3 class="Heading">
Lisääntynyt suoliontelon sisältö, Increased Intraluminal Content</h3>
<div class="Para" id="Par6">
Suolen sisällä on kaasua, ilmaa, vettä ja ulosteeksi menevää materiaalia. Ilman ja kaasun määrä saattaa muodostua runsaaksi, kun nielee ilmaa ( aerophagia) ja mahdollisesti paksunsuolen tai ohutsuolen bakteerit tuottavat liikaa kaasua. Ohuensuolen bakteerien ylikasvu (SIBO), kaasujen liian vähäinen absorboituminen ja runsaasti fermentoituvaa huonostisulavaa ja imeytyvää hiilihydraattia sisältävä ravinto saattavat jokainen olla osatekijöitä. Kuitenkin tuoreet tutkimukset ovat osoittaneet, että IBS-potilaiden ja terveiden suoliston kaasupitoisuuksissa on olematon tai vain mitätön ero, jos he käyttävät samanlaiset määrät fermentoituvia hiilihydraatteja. Eräässä toisessa uudella mahan tietokonetomografia-metodilla tehdyssä tutkimuksessa ( Accarino et al) ei havaittu muutoksia mahan kokonaistilavuudessa vaikean pömpötysjakson aikana vertailtaessa perustilanteeseen. Sen takia - mainittuihin tutkimuksiin perustuen- on epätodennäköistä, että suolisto-ontelon sisällä oleva kaasu olisi taustalla päämekanismina FABD- oireiden kehittymisessä. </div>
<div class="Para" id="Par6">
<br /></div>
<ul>
<li>Intraluminal
content includes gas, air, water, and fecal material. Air and gas may
become abundant within the lumen through aerophagia and potentially from
overproduction of gas by colonic or small intestine bacteria [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR6" role="button" title="View reference">6</a></span>].
Small intestinal bacterial overgrowth (SIBO), gas underabsorption, and
diet high in fermentable, poorly digested and absorbed carbohydrates may
all play a role [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR7" role="button" title="View reference">7</a></span>].
However, recent studies have shown minimal, if any, differences in gas
contents between IBS and healthy controls who consumed similar amounts
of fermentable carbohydrates [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR8" role="button" title="View reference">8</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR9" role="button" title="View reference">9</a></span>].
In another study comparing gas contents using a novel abdominal CT
method, Accarino et al. did not find any change in the total abdominal
volume during episodes of severe bloating, compared to baseline [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR10" role="button" title="View reference">10</a></span>].
Therefore, on the basis of the mentioned studies, excessive
intraluminal gas is unlikely to be a major underlying mechanism for
symptom generation in FABD.</li>
</ul>
<h3 class="Heading">
Sisälmyksien yiiherkkyys, Visceral Hypersensitivity</h3>
<div class="Para" id="Par7">
Funktionaalista mahanpömpöty ja suolten laajentuma voi olla alkuisin suoliston herkkyyden kasvamisesta epätavallisen virinneessä huomionkiinnityksessä suoliontelon sisältöön. </div>
<div class="Para" id="Par7">
Tosiasiassa IBS- potilaat ovat tavallista valveutuneempia suolensa sisällön ja suoliston liikehdinnän suhteen ja saattavat kokea normaalin tai hieman muuntuneen suoliontelosisällön mahan pömpötyksenä. Malagelada et al. laajassa perusteellisessa katsauksessa käytti termiä " tietoinen havainnoiminen" selittäessääm aivo-suoli-akselin osuutta oireiden kehkeytymisessä ( mahan pömpötyksen tunteen muodostumisessa) . Tämän mallin mukaan sisälmysperäinen allodynia, kivuliaisuus (jota on myös IBS-taudissa) vastaa mahapömpötyksen kokemisesta, mitä tapahtuu normaalista tai aivan lievästi lisääntyneestä suolistokaasusta tai suolensisällöstä johtuen .</div>
<div class="Para" id="Par7">
<br /></div>
<ul>
<li>Functional
abdominal bloating and distension may originate from increased gut
sensitivity and abnormally increased attention to intraluminal contents.
In fact, patients with IBS have an increased awareness of their gut
contents and motility, and may experience normal or slightly altered gut
intraluminal content as bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR11" role="button" title="View reference">11</a></span>].
In their comprehensive review, Malagelada et al. used the term
“conscious perception” to explain the role of the brain–gut axis in
symptom generation (abdominal bloating). According to this model,
visceral allodynia (seen also in IBS) is responsible for the bloating
sensation that occurs in the presence of normal or only mildly increased amounts of intraluminal gas or other bowel content [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span><span class="CitationRef"></span> </li>
</ul>
<h3 class="Heading">
Abdominofrenikaali dyssynergia, maha-palleahermojen- yhteistoimintahäiriö. </h3>
<h3 class="Heading">
Abdomino Phrenic Dyssynergia</h3>
Tämä käsite, joka kiteytettiin Barcelona-ryhmässä, kuvaa FABD- potilaiden vastetta ateriaan. </div>
<div class="resc">
Ryhmän tutkimusten mukaan FABD- potilailla oli epätavallista lihasaktiivsuutta, jota luonnehti mahan etuseinämän relaksoituminen (rentoutuminen) ja pallean (diaphragma) kontrahoituminen (supistuminen). Tällainen aktiivisuus tekee mahakaasuille uudenlaisen jakautuman ja sen takia aiheuttaa vatsan etuseinämän työntymisen eteenpäin. mikä on sitä havaittavaa suolen laajentumaa. Tämä on päinvastaista kuin terveillä kontrollihenkilöillä, joilla tapahtuu aterian symisen yhteydessä mahan etuseinämän supistuma ja pallean relaksaatio. Tämän paradoksaalisen manööverin syy FABD:ssä ei ole täysin käsitettyä. Se saattaa olla suhteessa viskerosomaattisiin vasteisiin vaarattomille suolensisäisille ärsykkeille, joissa aivo-suoli-akseli on osallisena. Oli syy mikä tahansa niin abdomino-frenikaalinen dyssynergia edustaa uutta ja päämekanismia, joka pystynee selittämään FABD- tapauksia. </div>
<div class="resc">
<br /></div>
<div class="resc">
<ul>
<li>This
term, coined by the Barcelona group, describes the response of patients
with FABD to a meal. According to studies by the group, patients with
FABD have an abnormal muscle activity characterized by anterior
abdominal wall relaxation and diaphragm contraction. This activity
redistributes abdominal gas, thereby causing an anterior wall protrusion
and visible distension. This is in contrast to healthy controls who in
response to a meal experience contraction of anterior abdominal wall
muscles and relaxation of the diaphragm [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR10" role="button" title="View reference">10</a></span>].
The reason for this paradoxical maneuver in FABD is not completely
understood. It may be related to an abnormal viscero-somatic response to
innocuous intraluminal stimuli involving the brain–gut axis. Regardless
of its cause, the description of abdomino-phrenic dyssynergia
represents a novel and major mechanism that may explain the occurrence
of FABD [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>]. </li>
</ul>
</div>
<div class="resc">
<h3>
Ummetus ja ulosvirtauksen tukos, Constipation and Outflow Obstruction</h3>
<section class="Section2 RenderAsSection2" id="Sec7" tabindex="-1"><div class="Para" id="Par9">
Funktionaalinen mahanpömpötys ja suolilaajentuma saattaa olla suhteessa ummetukseen ja suolen sisällön virtauksen tukokseen. Jos uloste jää paikoilleen peräsuoleen, voi aiheutua kaasujen poistumisen vaikeutumista ja suolen läpikulun hidastumista. Verrattaessa terveisiin vapaaehtoisiin FABD- potilailla oli paksunsuolen läpikulku hitaampaa. Kontrolloiduissa sokkokokeissa osoittautui ,että lubiprostone -tai linaclotide - lääkkeillä hoidetut ummetusoireiset IBS- potilaat kokivat merkittävää parantumista mahan pömpötysoireista.. Edelleen funktionaalisessa suolisisällön virtaustutkimuksissa suolen sisällön poistumiskokeen huono tulos korreloi FABD:hen. </div>
<div class="Para" id="Par9">
<ul>
<li>Functional
abdominal bloating and distension may be related to constipation and to
functional outflow obstruction. Retained stool in the rectum may cause
impaired gas evacuation and slowing of intestinal transit [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR13" role="button" title="View reference">13</a></span>]. Compared with healthy volunteers, patients with FABD have a slower colonic transit [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR14" role="button" title="View reference">14</a></span>].
Randomized controlled trails show that patients with
constipation-predominant IBS (IBS-C) treated with lubiprostone or
linaclotide experience a significant improvement in bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR15" role="button" title="View reference">15</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR16" role="button" title="View reference">16</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR17" role="button" title="View reference">17</a></span>].
Furthermore, among patients with functional outlet obstruction
(dyssynergia), prolonged balloon expulsion correlates with the presence
of FABD [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR18" role="button" title="View reference">18</a></span>].</li>
</ul>
</div>
</section><section class="Section2 RenderAsSection2" id="Sec8" tabindex="-1"><h3 class="Heading">
Liikapainoisuus, Obesity</h3>
<div class="Para" id="Par10">
Nopea painon nousu tai vastaavasti lasku assosioituvat pahenemaan ja vastaavasti parantumaan suolen pömpötyksessä. Yhdessä tutkimuksessa tuore painonnousu asettui ajallisesti yhteen uuden pömpötysepisodin alkuun 25%:ssä prosentissa osallistujista. Eräässä mahdollisessa mekanismissa saatata olla osallisena epänormaali viskero-somaattinen refleksi, alkuisin vatsan rasvakudoksesta, joka moduloi aivosuoli-akselia. ja johtaa FABD:hen. <br />
<br />
<ul>
<li>Rapid weight gain and weight loss are associated with aggravation and improvement in bloating, respectively [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>]. In one study, recent weight gain coincided with new onset bloating in 25% of the participants [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR5" role="button" title="View reference">5</a></span>].
A possible mechanism may involve an abnormal viscero-somatic reflex
originating in the abdominal adipose tissue which modulates the
brain–gut axis, resulting in FABD [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR19" role="button" title="View reference">19</a></span>].</li>
</ul>
</div>
</section><br />
<br />
<section class="Section2 RenderAsSection2" id="Sec10" tabindex="-1"><h3 class="Heading">
Psykologiset samanaikaissairaudet, Psychological Comorbidities</h3>
<div class="Para" id="Par12">
Ei ole perin pohjin tutkittu psykologisten samanaikaissairauksien ja FABD:n välistä suhdetta.<br />
Siitä huolimatta on ehdotettu, että stressi saataisi antaa osansa lisääntyneesenn tietoisuuteen mahan pömpötyksestä. Eräästä tutkimuksesta saatiin tietää, että mahanpömpötysoireisilta naisilta oli raportoitu anamneesissa usein depressiota ja rauhattomuutta. <br />
<ul>
<li>The
relationship between psychological comorbidities and FABD has not been
fully investigated. Nevertheless, it has been suggested that stress may
contribute to increased perception of abdominal bloating. In one study
it was reported that women with bloating frequently reported a history
of depression and anxiety [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR25" role="button" title="View reference">25</a></span>].</li>
</ul>
</div>
</section><br />
<br />
<section class="Section2 RenderAsSection2" id="Sec9" tabindex="-1"><h3 class="Heading">
Mikrobiomihäiriö, dysbioosi, Dysbiosis</h3>
<div class="Para" id="Par11">
Paksunsuolen mikrobiomin poikkeva koostuminen tai muuntuminen voi johtaa lisääntyneeseen paksunsuolen kaasujen tuotantoon fermentaatiosta tai vähentyneeseen kaasun kulutukseen, mikä johtaa paksunsuolen kaasumäärän lisääntymiseen ja pömpötyksen tunteeseen. Collins et al. havaitsivat, että isäntäkehon mikrobiomin tasapainon keskeytyminen vaikuttaa suoliston immuunijärjesetlmään ja johtaa tulehdukseen. Tämä puolestaan jothaa suolen sensoriseen ja motoriseen vikatoimintaan, jota voi suolenpömpötyksessä esiintyä.<br />
Toiset ovat tehneet huomion, että paksunsuolen flooran ja paksunsuolen kaasun kemiallisten komponenttien kesken on suhde. Sorbitolin ja kuidun nauttimisen jälkeen on havaittu metaania heikosti tuottavien aiheuttavan enemmän pömpötystä. IBS- potilaiden ulostenäytteiden molekulaarinen analyysi ei ole onnistunut osoittamaan mitään yhtenäistä koostumusta IBS- mikrobiomille., mutta paljasti Firmicutes/Bacteroides lajien välisen suhteen kasvaneen. IBS- potilaskohortin mikrobiomitutkimuksista Ringel-Kulka et al on havainnut assosiaatiota suolimikrobiomin, mahan pömpötyksen ja muuntuneiden suolistotoimintojen kesken. Hän huomasi merkitseviä muutoksia mikrobiomissa IBS- taudin eri alatyypeissä. Erityinen löytö oli se, että mahanpömpötysoire liittyi mikrobitaxonomian sopesifisiin ryhmiin. <br />
<br />
<ul>
<li>Aberrant
constitution or alteration in colonic microbacteria may lead to
increased production of colonic gas by fermentation or decreased gas
consumption, leading to increased colonic gas content and bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR20" role="button" title="View reference">20</a></span>].
Collins et al. found that interruption of the host–microbiota
equilibrium affects the intestinal immune system and leads to
inflammation. This, in turn, leads to gut sensory and motor dysfunction
which may contribute to bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR21" role="button" title="View reference">21</a></span>].</li>
<li> Others have noted a relationship between colonic flora and the chemical
composition of colonic gas. An interesting finding is that low
producers of methane describe increased bloating following ingestion of
sorbitol and fiber [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR22" role="button" title="View reference">22</a></span>].
Molecular analysis of fecal samples from IBS patients have failed to
demonstrate a clear unifying texture for the IBS microbiome, but have
revealed an increased ratio of <i class="EmphasisTypeItalic ">Firmicutes</i> to <i class="EmphasisTypeItalic ">Bacteroidetes</i> species [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR23" role="button" title="View reference">23</a></span>].
More recently, Ringel-Kulka et al. investigated the relationship
between the intestinal microbiota, abdominal bloating, and altered bowel
patterns in a cohort of patients with IBS and found significant changes
in microbiota among different IBS subtypes. In particular, the authors
noted that bloating was associated with specific microbial taxa [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR24" role="button" title="View reference">24</a></span>].</li>
</ul>
</div>
</section></div>
<div id="ncbi_share_pm">
<br />
<section class="Section2 RenderAsSection2" id="Sec14" tabindex="-1"><h2 class="Heading">
Suomenos jatkuu..</h2>
<h2 class="Heading">
22.9.2019 </h2>
<h2 class="Heading">
</h2>
<h2 class="Heading">
Evaluation</h2>
<div class="Para" id="Par13">
As
for any other medical condition, evaluation starts with a detailed
medical history, physical examination, and appropriate diagnostic tests.
As mentioned, it is crucial to exclude any organic cause for bloating
and distention, including celiac disease or any other malabsorptive
disorder, gut dysmotility, and chronic intestinal pseudo-obstruction.
Common organic etiologies responsible for abdominal bloating and
distension are described in Table <span class="InternalRef"><a href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#Tab1">1</a></span>.</div>
<div class="Para" id="Par14">
In
addition, the presence of alarm signs, such as weight loss, rectal
bleeding, or anemia, should be investigated immediately. History taking
should focus on diurnal changes, relationship to certain foods or food
components (dairy products, wheat, fructans, fat, fiber, poorly digested
and absorbed carbohydrates), and change in bowel habits. The severity
of FABD is often lowest in the morning/night and greatest post-prandial
(after breakfast) and during the early evening [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR26" role="button" title="View reference">26</a></span>].
Symptoms suggestive of an overlap with IBS, functional dyspepsia, or
functional constipation should be recorded as well. A concurrent
diagnosis of another FGID often changes treatment modalities.</div>
<div class="Para" id="Par14">
A physical exam may reveal an increase in abdominal girth and signs of bowel
obstruction. Rectal and pelvic examination should be performed in
constipated patients. Abdominal distention may be objectively assessed
by abdominal inductance plethysmography, an ambulatory device that can
continuously measure patients’ abdominal girth [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR27" role="button" title="View reference">27</a></span>].
Although there are no validated guidelines for the evaluation of FABD,
the Rome IV 2016 working group recommends basic diagnostic tests such as
complete blood count (CBC) if anemia is suspected, celiac serology (and
if positive, duodenal biopsies should be added), abdominal x-ray to
rule out obstruction, and a breath test for the diagnosis of SIBO [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR28" role="button" title="View reference">28</a></span>].</div>
<h2 class="Heading">
</h2>
<h2 class="Heading">
Treatment</h2>
<div class="content">
<div class="Para" id="Par16">
After
the exclusion of alarm signs, organic disease, and overlap with other
FGID, the next step is to offer a stepwise, individualized treatment as
described in Fig. <span class="InternalRef"><a href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#Fig1">1</a></span>.
Patients with mild functional bloating may need merely reassurance that
the condition is benign and does not herald any life-threatening
disease.</div>
</div>
<h3 class="Heading">
</h3>
<h3 class="Heading">
Symptomatic Treatment</h3>
<div class="Para" id="Par17">
Several
agents are available for the treatment of FABD. Antispasmodics have
shown some clinical benefit in symptoms relief in some patients [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>]. Simethicone was found to reduce the frequency and severity of gas, distention, and bloating in a double-blind trial [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR29" role="button" title="View reference">29</a></span>]. In two other controlled trials, peppermint oil significantly reduced distention compared to placebo [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR30" role="button" title="View reference">30</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR31" role="button" title="View reference">31</a></span>].
Despite their popularity, evidence is lacking in regard to other
commonly used agents such as activated charcoal, Iberogast, and
magnesium salts.</div>
<h3 class="Heading">
</h3>
<h3 class="Heading">
Dietary Intervention</h3>
<div class="Para" id="Par18">
The
role of dietary therapy in the management of bloating symptoms is
crucial and generally introduced early in the treatment plan. The main
rationale of dietary therapy is to identify foods to which the patient
is intolerant and thereby reduce excessive fermentation of food
residues. Empiric restriction of lactose and other poorly absorbed
carbohydrates may be initially performed [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>].
Alternatively, a low FODMAP (fermentable oligosaccharides,
disaccharides, monosaccharides, and polyols) diet and other elimination
diets may be offered to patients with FABD who have failed restriction
diets [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR32" role="button" title="View reference">32</a></span>].
In our opinion, diet interventions with restrictive diets should be
delivered by trained dieticians who closely collaborate with the
clinician. This approach may increase the patient’s compliance and
reduce the risk of nutritional deficiencies. It should be noted that an
over-restrictive diet may in and of itself alter the colonic microbiota
with undesired consequences [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR33" role="button" title="View reference">33</a></span>].
Although unproven, in certain cases it seems appropriate to assess
objectively the presence of carbohydrate intolerances by performing the
corresponding breath tests [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>].</div>
</section></div>
<div id="ncbi_share_pm">
<h3 class="Heading">
Relief of Constipation</h3>
<div class="Para" id="Par19">
Patients
with chronic idiopathic constipation (CIC) and IBS-C commonly report of
bloating. Lubiprostone, a chloride channel agonist, was found to
decrease bloating in two placebo-controlled clinical trials that
enrolled patients with IBS-C [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR16" role="button" title="View reference">16</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR34" role="button" title="View reference">34</a></span>]. Prucalopride, a selective 5-HT<sub>4</sub> receptor agonist, was found to increase spontaneous bowel movements and to reduce bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR35" role="button" title="View reference">35</a></span>].
Similarly, linaclotide, a guanylate cyclase C agonist, was found to
improve constipation (increased spontaneous bowel movements) and to
reduce abdominal pain and bloating in patients with CIC and IBS-C [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR36" role="button" title="View reference">36</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR37" role="button" title="View reference">37</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR38" role="button" title="View reference">38</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR39" role="button" title="View reference">39</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR40" role="button" title="View reference">40</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR41" role="button" title="View reference">41</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR42" role="button" title="View reference">42</a></span>].</div>
<div class="Para" id="Par20">
Finally,
in one small placebo-controlled clinical trial, intravenous
administration of neostigmine was found to enhance clearance of infused
jejunal gas in a cohort of patients with abdominal bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR43" role="button" title="View reference">43</a></span>].
However, in another trial of IBS patients with bloating, it was found
that pyridostigmine provided only a minimal effect on symptoms [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR44" role="button" title="View reference">44</a></span>].</div>
<br />
<section class="Section2 RenderAsSection2" id="Sec16" tabindex="-1"><h3 class="Heading">
Microbiome Modulation</h3>
<div class="Para" id="Par21">
Reducing
gas-producing bacteria or causing alterations of their metabolic
activities may decrease excessive fermentation and bloating. Rifaximin, a
poorly absorbed broad-spectrum antibiotic, was found to improve
bloating and flatulence in controlled trials in patients with and
without IBS [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR45" role="button" title="View reference">45</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR46" role="button" title="View reference">46</a></span>].
Probiotics may become a therapeutic option in FABD; however, studies
have revealed mixed results, probably due to the lack of standardized
study methods [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR47" role="button" title="View reference">47</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR48" role="button" title="View reference">48</a></span>]. In a recent review, it was suggested that probiotics have a role in the treatment of functional gastrointestinal disorders [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR49" role="button" title="View reference">49</a></span>]. In a double-blind study by Ringel et al. it was shown that <i class="EmphasisTypeItalic ">Lactobacillus acidophilus</i> and <i class="EmphasisTypeItalic ">Bifidobacterium lactis</i> Bi-07 improved bloating in non-constipated patients with FGID [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR50" role="button" title="View reference">50</a></span>].</div>
</section><br />
<h3 class="Heading">
Abdominal Biofeedback Therapy</h3>
</div>
</div>
As pr eviously described, post-prandial FABD may
result from abnormal anterior abdominal wall relaxation and
diaphragmatic contraction. These behaviors cause a redistribution of
intrabdominal gas, resulting in an anterior wall protrusion and visible
distension [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR10" role="button" title="View reference">10</a></span>].<br />
<div class="Para" id="Par23">
The
explanation for these behaviors may be related to an abnormal
viscero-somatic reflex, causing a thoraco-abdominal striated muscular
activity that reshapes the abdomen and pushes it to protrude anteriorly [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>].
This abnormal reflex activity or behavior is potentially amenable to
biofeedback therapy. In fact, Barba et al. showed that it is possible to
educate patients on how to use their abdominal and diaphragmatic
muscles [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR51" role="button" title="View reference">51</a></span>].
FGID patients with distension were randomized to biofeedback or
placebo. Biofeedback sessions were offered on separate days up to three
times during a 1- to 2-week period [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR51" role="button" title="View reference">51</a></span>].
Biofeedback effectively diminished diaphragmatic and intercostal muscle
contraction, decreasing both subjective bloating and abdominal girth [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR51" role="button" title="View reference">51</a></span>].
These findings suggest that FABD may be improved by performing
diaphragmatic or abdominal breathing. This simplification of biofeedback
training, 5 min before and 5 min after meals, effectively relaxes the
intercostal muscles and the diaphragm while contracting the anterior
abdominal muscles [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR51" role="button" title="View reference">51</a></span>].</div>
<br />
<section class="Section2 RenderAsSection2" id="Sec18" tabindex="-1"><h3 class="Heading">
Modulating the Brain–Gut Axis</h3>
<div class="Para" id="Par24">
If
an amplified perception of bowel wall stretch and visceral
hypersensitivity are key components in the pathogenesis of FABD, then
modulating the brain–gut axis seems to be a reasonable treatment option.
Antidepressants, such as tricyclic antidepressant (TCA) and selective
serotonin reuptake inhibitors (SSRIs) and selective noradrenalin
reuptake inhibitors (SNRI), were evaluated in patients with IBS.
However, their exact role of these antidepressants in improving bloating
symptoms is unclear [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR52" role="button" title="View reference">52</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR53" role="button" title="View reference">53</a></span>].
In a small, controlled crossover study, citalopram (an SSRI) showed an
increase in the number of days without bloating at 3 and 6 weeks [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR53" role="button" title="View reference">53</a></span>].</div>
<div class="Para" id="Par25">
In another study, desipramine (TCA) combined with cognitive behavioral therapy decreased bloating [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR54" role="button" title="View reference">54</a></span>].
Hypnotherapy and cognitive behavioral therapy, which are commonly
offered to patients with IBS, may also be effective in patients with
FABD [<span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR12" role="button" title="View reference">12</a></span>, <span class="CitationRef"><a aria-controls="popup-references" aria-expanded="false" href="https://link.springer.com/article/10.1007%2Fs12325-019-00924-7#CR55" role="button" title="View reference">55</a></span>].</div>
</section>authors Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-1175678574742824992019-03-04T22:06:00.001+01:002019-03-04T22:10:01.442+01:00Puolukan eduista väitöskirjatietoa Helsingin Yliopistosta <a href="https://helda.helsinki.fi/handle/10138/299571">https://helda.helsinki.fi/handle/10138/299571</a><br />
Tri Jenny Westerlinin abstrakti aiheesta:<br />
Sitaatti: " Kielisyöpä luokitellaan suuontelon syöpiin, jotka ovat yleisimpiä pään
ja kaulan alueen syöpiä. Kielisyövällä on useita altistavia ja suojaavia
tekijöitä. Terveellisten elintapojen on esimerkiksi osoitettu suojaavan
syövältä, ja ruokavaliossa kasvikset ja vihannekset vähentävät
syöpäriskiä merkittävästi.<b> Puolukka</b> sisältää erilaisia
polyfenoliyhdisteitä, joiden on todettu muun muassa vaikuttavan solun
sisäisiin signaalireitteihin ja suojaavan soluja oksidatiiviselta
stressiltä.
Tutkielmani hypoteesina oli, että puolukkauute vähentää
kielisyöpäsolujen jakaantumista eli proliferaatioita in vitro.
Laboratoriokokeissani analysoin kahta kaupallista kielisyöpäsolulinjaa
(SCC-25 ja HSC-3). Käytin kolmea eri fermentoidun puolukkauutteen
(Fermented Lingonberry Juice, FLJ) konsentraatioita (500 μg/ml, 2500
μg/ml ja 5000 μg/ml) ja vertasin eri uutemäärien vaikutusta
kontrollisolujen jakaantumiseen. Proliferaatiota tutkin enzyme linked
immunosorbent assay, eli ELISA-menetelmällä BrdU-merkkiaineen avulla
käyttäen Cell proliferation, ELISA BrdU -kittiä. Analysoin tulokset
mittaamalla solujen lukumäärää kuvaavat absorbanssiarvot ja tein
tuloksista tilastolliset analyysit.
<b>Puolukkauute vähensi merkitsevästi suurempina (2500 μg/ml ja 5000 μg/ml)
pitoisuuksina molempien kielisyöpäsolulinjojen proliferaatiota. </b>
Solulinjojen välillä oli eroa siten, että FLJ teho oli suurempi vähemmän
aggressiiviselle SCC-25 solulinjalle kuin selkeästi aggressiivisemmalle
HSC-3 solulinjalle.
Yhteenvetona voin todeta, että puolukkauute vähensi
kielisyöpäsolulinjojen jakaantumista in vitro mahdollisesti marjassa
olevien polyfenoliyhdisteiden ansiosta. <b>Tarkka mekanismi puolukan
sisältämien yhdisteiden vaikutuksesta syöpäsolujen jakaantumisen
ehkäisemisessä ei kuitenkaan ole vielä selvillä, vaan lisätutkimusta
molekyylitason mekanismien selvittämiseksi tarvitaan. </b><br />
<br />
<b>Puolukka, Lingon</b><br />
<b><i><b>Vaccinium vitis-idaea</b></i> (<b>lingonberry</b>, <b>partridgeberry</b>, <b>mountain cranberry</b> or <b>cowberry</b>) </b><br />
<b>Haku PubMed Partridgeberry ( 5) </b><br />
<br />
<div class="title_and_pager">
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/28411989"><b>Partridgeberry</b> polyphenols protect primary cortical and hippocampal neurons against β-amyloid toxicity.</a></div>
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Bhullar KS, Rupasinghe HPV.</div>
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<span class="jrnl" title="Food research international (Ottawa, Ont.)">Food Res Int</span>. 2015 Aug;74:237-249. doi: 10.1016/j.foodres.2015.05.019. Epub 2015 May 11.</div>
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/25941748"><b>Partridgeberry</b>
polyphenols protect rat primary cortical neurons from oxygen-glucose
deprivation-reperfusion-induced injury via suppression of inflammatory
adipokines and regulation of HIF-1α and PPARγ.</a></div>
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Bhullar KS, Rupasinghe HP.</div>
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<span class="jrnl" title="Nutritional neuroscience">Nutr Neurosci</span>. 2016 Jul;19(6):260-8. doi: 10.1179/1476830515Y.0000000026. Epub 2015 May 5.</div>
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/25172753">Antioxidant and cytoprotective properties of <b>partridgeberry</b> polyphenols.</a></div>
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Bhullar KS, Rupasinghe HP.</div>
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<span class="jrnl" title="Food chemistry">Food Chem</span>. 2015 Feb 1;168:595-605. doi: 10.1016/j.foodchem.2014.07.103. Epub 2014 Jul 30.</div>
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/15264904">Resveratrol, pterostilbene, and piceatannol in vaccinium berries.</a></div>
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Rimando AM, Kalt W, Magee JB, Dewey J, Ballington JR.</div>
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<span class="jrnl" title="Journal of agricultural and food chemistry">J Agric Food Chem</span>. 2004 Jul 28;52(15):4713-9.</div>
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/15124322">Herbal friend for birthing mothers: <b>partridgeberry</b>.</a></div>
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Perri S.</div>
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<span class="jrnl" title="Midwifery today with international midwife">Midwifery Today Int Midwife</span>. 2004 Spring;(69):36. Review. No abstract available. </div>
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<b> </b>Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-76112584451593487042019-01-24T21:52:00.002+01:002019-01-24T21:52:40.527+01:00Suomen Antioksidanttiklinikkojen perustaja Kaarlo Jaakkola Olin opiskeluaikanani lomilla töissä kristiinassa kirurgian osaston apulaislääkärinä 1960 luvulla. Osasonlääkäri oli kaarlo jaakkola ja hän teki runsaasti leikkauksia, varinkin sappileikkaukset ja suonikohjuleikkaukset oliat yleisiä akuuttien operaatioiden lisäksi.<br />
Siellä sain tietää jo niihin aikoihin jotain hivenainekiinnostuksesta. ihmisillä oli nimittäin erittäin huono ihon paraneminen, tihkuvia ja ödemaisia ihoja. jaakkola oli tullut siihen tulokseen että kyseessä on kehojen ravintoaineissa jotain aivan olennaista vikaa. Kirurgille merktisee paljon, että kehon kudokset ja iho alkavat "normaalisti" parantua ja ovat konsistenssiltaan normaaleita.<br />
Nyt onkin siten saatu selville jo paljon syitä, miksi suomalisten konsistenssi on ollut niin huononlaatuista - on löydetty ravintotekijöitä kuten laktoosi-intoleranssi, hyperkolesterolemia, keliakian yleisyys . Myös ravintotilanne on aprantunut. On tullut paljon kasvisöljyjä käyttöön ja samoin tietoisuus omega-3 kalahapoista. Nämä jo itsessään normalisoivat kehoa.<br />
Mineraalivajeitten ollessa sitä luokkaa mitä 1960-1970 luvulla- alkoholin osuudesta kansanravinnosssa ja mineraalien tyhjentäjänä puhumattakaaan - alkuapuna on ollut mineraalivalmisteiden käyttö. lisäksi tupakan loeptatmisella on ollut suurta merkitystä .<br />
<br />
Jaakkola on Suomen pioneeri tällä alalla.<br />
Alansa Aleksis Kivi.<br />
Työalue on laaja eikä vastustajia puutu kuten Paavali sanoi aloittaessaan pakanlähetystyön Euroopassa. <br />
<br />
https://yle.fi/aihe/artikkeli/2000/05/15/pehmeita-hoitoja-kovaa-rahastusta-kasikirjoitus<br />
<br />
<br />
<br />
<br />
<br />
<br />Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-17545934169411381462019-01-07T01:12:00.001+01:002019-01-07T01:23:25.929+01:00Goji, Lycium barbarum ( Wolfberry) Pukinpensas , Bocktörne <a href="https://www.sciencedirect.com/science/article/pii/S0308814616311384?via%3Dihub">https://www.sciencedirect.com/science/article/pii/S0308814616311384?via%3Dihub</a><br />
<a href="https://fi.wikipedia.org/wiki/Pukinpensas"> https://fi.wikipedia.org/wiki/Pukinpensas</a><br />
<a href="https://sv.wikipedia.org/wiki/Bockt%C3%B6rne">https://sv.wikipedia.org/wiki/Bockt%C3%B6rne</a><br />
<br />
Näyttää siltä että Goji-marjoilla on solua korjaavan marjan maine Suomessakin.<br />
Otan tästä yhden nettiesimerkin.<br />
<a href="https://kuntoplus.fi/terveellinen-ruokavalio/superfood/ihonhoito-gojimarja-korjaa-soluja"> https://kuntoplus.fi/terveellinen-ruokavalio/superfood/ihonhoito-gojimarja-korjaa-soluja</a><br />
<br />
Kiinassa Gojimarja on yhtenä komponenttina Kang Fu Ling-nimisessä yrttiseoksessa, joka auttaa korjaamaan sydänlihaksen HPM- altistusvauriota _ PubMed artikkelin mukaan. Kyse on lähinnä mitokondriaalisen tilanteen koehntamiessa, sillä HPM vaikutata soluturvotusta, mitokondrian membraanipotentiaalin alenemista ja kalsiumin pääsyä sytoplasmaan. Sähkökäyrässä vaikutus HPM- vauriosta ei näy T-aaltomuutoksena, vaan J-pisteessä. <br />
6.1. 2018Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-63962230745987469642018-11-20T12:26:00.001+01:002018-11-20T12:55:31.785+01:00Persimoni antaa vitamineraaleja. A-vitamiinia ja karotenoideja mukavasti <a href="https://www.totalproducenordic.se/everfresh/sv/produkter/Frukt/Druvor2/SharonPersimonKaki/">https://www.totalproducenordic.se/everfresh/sv/produkter/Frukt/Druvor2/SharonPersimonKaki/</a><br />
Kuvassa on PERSIMON. Israelin vastaava hedelmä on jalostettu, sikäli että siinä ei ole parkkihappoja, jotka persimonista katoavat vasta kun se on täysin kypsä. Sharonhedelmä on myös siemenettömämpi ja sen voi syödä jo ennen kuin se on ylikypsä. Nämä hedelmät persimon, kaki, ja Sharon kuuluvat ebonipuuheimoon Ebenaceae, sukuun Diospyros. Kts. engl. selvitys taxonomiasta lopussa. <br />
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg547ePeVnIj3QZj900ngGQmm3FGUMrUPIPI5vYdh6KVS-YptMMdxmEn4ZcRKwHgA8gNV3D_VoP5ydYi3NqM7ZZR7xyYQ2YbWNN3PKfx6NgGGfC5q34QLF85nDels8nz4xIGgM_D-lD74GM/s1600/IMG_1269.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1200" data-original-width="1600" height="240" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg547ePeVnIj3QZj900ngGQmm3FGUMrUPIPI5vYdh6KVS-YptMMdxmEn4ZcRKwHgA8gNV3D_VoP5ydYi3NqM7ZZR7xyYQ2YbWNN3PKfx6NgGGfC5q34QLF85nDels8nz4xIGgM_D-lD74GM/s320/IMG_1269.JPG" width="320" /></a></div>
<br />
Sitaatti <br />
<h3>
Sharon/Persimon/Kaki (Svenska) </h3>
Frukten påminner till utseendet om en tomat, men skiljer sig genom de
4 stora foderbladen. Färgen kan vara gul- eller röd-orange. Skal och
fruktköttet har samma färg. Frukten är indelad i upp till 8 rum. När den
är fullmogen är köttet genomskinligt och har mjuk, nästan flytande
konsistens. Skalet är tunt som hos tomat. Kan ätas, kan upplevas som
segt och då kan den skala. Smaken är söt, fyllig och påminner något om
söta plommon och dadlar. De flesta typer är kärnfria. <br />
Några
persimon- och kakisorter innehåller i omoget tillstånd en <b>garvsyra.</b> Den
bryts ner under mognaden och dessa typer är därför inte ätliga innan
frukten är helt mogen och mjuk.<br />
Sharonfrukter är persimon/kaki som
vidareutvecklats i Israel. Dessa frukter saknar bitterämnen, och kan
ätas direkt efter skörd. Smaken är söt och fyllig. Ibland skiftar
fruktköttet i brunt, vilket är en sockerutfällning. Det försämrar inte
kvaliteten på frukten. Frukterna kan förvaras kallt, 0-4 grader. Omogna
frukter mognar i rumstemperatur. Mogna är mycket känsliga för tryck och
klämskador och bör lagras så kort tid som möjlig.<br />
<br />
<div class="panel-heading" id="VITAM-heading" role="tab">
<div class="segment segment-3">
<a aria-controls="VITAM" aria-expanded="true" class="" data-parent="#accordion" data-toggle="collapse" href="https://fineli.fi/fineli/fi/elintarvikkeet/33038?q=kaki&foodType=ANY&portionUnit=G&portionSize=100&sortByColumn=name&sortOrder=asc&component=2331&#VITAM" role="button">
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<div class="segment segment-1">
Vitamiinit FINELI FI (suomeksi; löytyy kyllä engl. ja ruotsiksi samasta lätheestä www.finlei.fi) </div>
<div class="segment segment-1">
Sharon, Persimon, Kaki, 100g </div>
<div class="segment segment-1">
<br />
<table class="table components"><thead>
<tr><th>Määrä</th>
<th>Menetelmä</th>
<th>Tietolähde</th>
<th>Julkaisu</th>
</tr>
</thead>
<tbody>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2023">kalsium</a></b></td>
<td><b>
8.0 mg
</b></td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2160">rauta</a></td>
<td>0.2 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2192">kalium</a></b></td>
<td><b>
161.0 mg
</b></td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2212">magnesium</a></b></td>
<td><b>
9.0 mg
</b></td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2216">natrium</a></td>
<td>1.0 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2217">suola</a></td>
<td>2.5 mg
</td>
<td>laskettu kertoimilla
</td>
<td>THL:n tuottama
</td>
<td></td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2223">fosfori</a></b></td>
<td><b>
17.0 mg
</b></td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2244">seleeni</a></td>
<td>1.0 µg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2282">sinkki</a></td>
<td>0.1 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a></td></tr>
</tbody></table>
</div>
<div class="segment segment-1">
</div>
<div class="segment segment-1">
</div>
</div>
<table class="table components"><thead>
<tr>
<th><span class="sr-only">Ravintotekijä</span></th>
<th>Määrä</th>
<th>Menetelmä</th>
<th>Tietolähde</th>
<th>Julkaisu</th>
</tr>
</thead>
<tbody>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2273"><b>folaatti,</b> kokonais-</a></td>
<td>8.0 µg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2275">niasiiniekvivalentti NE</a></td>
<td>0.2 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2291">niasiini (nikotiinihappo + nikotiiniamidi)</a></td>
<td>0.1 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2276">pyridoksiini vitameerit (vetykloridi) (B6)</a></td>
<td>0.02 mg
</td>
<td>laskettu kertoimilla
</td>
<td>THL:n tuottama
</td>
<td></td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2277">riboflaviini (B2)</a></td>
<td>0.02 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2278">tiamiini (B1)</a></td>
<td>0.03 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2269">B12-vitamiini (kobalamiini)</a></td>
<td>0 µg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2270">C-vitamiini</a></b></td>
<td>8.0 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2298">A-vitamiini RAE</a></b></td>
<td>107.1 µg
</td>
<td>summattu osatekijöistä
</td>
<td>THL:n tuottama
</td>
<td></td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2029">karotenoidit</a></b></td>
<td>1 290.0 µg
</td>
<td>summattu osatekijöistä
</td>
<td>THL:n tuottama
</td>
<td></td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2271">D-vitamiini</a></td>
<td>0 µg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><a href="https://fineli.fi/fineli/fi/ravintotekijat/2299">E-vitamiini alfatokoferoli</a></td>
<td>0 mg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1075">
1075
</a>
</td>
</tr>
<tr>
<td><b><a href="https://fineli.fi/fineli/fi/ravintotekijat/2274">K-vitamiini</a></b></td>
<td>2.60 µg
</td>
<td>muu arvon tyyppi
</td>
<td>elintarvikekoostumustaulukko
</td>
<td><a href="https://fineli.fi/fineli/fi/viitteet/1207">
1207 </a> </td></tr>
</tbody></table>
<br />
Englantilainen taksonomia:<br />
<br />
Diospyros-genuksessa on noin 500 löajia(species) eboniperheen puita ja pensaita, joko letensä tiputtavia tai ikivihreitä, useimmat voat peräisin tropiikista.<br />
<br />
<br />
<b>Diospyros</b>, <a class="md-crosslink autoxref" href="https://www.britannica.com/science/genus-taxon">genus</a> of some 500 <a class="md-crosslink autoxref" href="https://www.britannica.com/science/species-taxon">species</a> of trees and shrubs of the <a class="md-crosslink autoxref" href="https://www.britannica.com/topic/ebony-wood">ebony</a> family (Ebenaceae), either deciduous or <a class="md-crosslink autoxref" href="https://www.britannica.com/plant/evergreen-plant">evergreen</a>,
most of which are native to the tropics. The leaves, which lack teeth,
are usually borne alternately on opposite sides of the twig. The <a class="md-crosslink autoxref" href="https://www.britannica.com/science/fruit-plant-reproductive-body">fruit</a>
is a large juicy berry with 1 to 10 seeds. Some members of the genus
are valuable for their timber, particularly several species of ebony.
Others are <a class="md-dictionary-link" data-term="cultivated" href="https://www.merriam-webster.com/dictionary/cultivated">cultivated</a> for their handsome foliage or edible fruit. Chief among the latter are the common, or <span id="ref282116"></span><a class="md-crosslink" href="https://www.britannica.com/plant/American-persimmon">American</a>, <a class="md-crosslink autoxref" href="https://www.britannica.com/plant/persimmon">persimmon</a> (<i>D. virginiana</i>), native to <a class="md-crosslink autoxref" href="https://www.britannica.com/place/North-America">North America</a>, and the <span id="ref282117"></span><a class="md-crosslink" href="https://www.britannica.com/plant/Japanese-persimmon">Japanese</a>, or kaki, persimmon (<i>D. kaki</i>), native to China but widely cultivated in other temperate regions. The globular orange fruit of <i>D. virginiana</i> is about 4 cm (1.5 inches) in diameter. The <a class="md-crosslink autoxref" href="https://www.britannica.com/plant/tree">tree</a> grows about 10 to 12 metres (33 to 40 feet) tall and bears yellowish white, bell-shaped flowers. <i>D. kaki</i>
grows 12 metres (39 feet) tall or more and bears yellowish white
flowers and orange-red fruit about 7.5 cm (3 inches) in diameter.
Several hundred varieties of <i>D. kaki</i> have been developed. Other species include the date plum (<i>D. lotus</i>), the black sapote (<i>D. digyna</i>), and the mabola (<i>D. discolor</i>), the last being cultivated for its tasty fruit, which is dark red to purple.<br />
<br />
<br />
20.11. 2018 Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-62764161600372919032018-11-18T18:06:00.000+01:002018-11-18T18:20:54.518+01:00Passiflora-hedelmän antioksidanteista PASSIOHEDELMÄ Passiflora edulis . Tämän kuvan otin kadunvarrelta Haifassa toukokuussa 2017.<br />
Näitä Passiflora penrai oli siellä täällä yksityistalojen puutarhoissa. Torikaupasta Akkossa sai ostaa vastapuristettua tuoretta passiflora- juissia jääpalojen kera hellepäivinä. Aivan ihana juoma! <br />
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhz3ly8rJI-8FxfEMdf0Q4bQb9vFX2htA3XHYLfO8FQKbjWVXLFz9QUnHzfpJHND8qIXyGGHZto179-h6yxn5ZgggvlsJg6ZnbjLt9CT-jTS7_sLh6FbpW5-aeQJgUG7lFSzWxmJdh74xq2/s1600/P5030159.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1200" data-original-width="1600" height="240" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhz3ly8rJI-8FxfEMdf0Q4bQb9vFX2htA3XHYLfO8FQKbjWVXLFz9QUnHzfpJHND8qIXyGGHZto179-h6yxn5ZgggvlsJg6ZnbjLt9CT-jTS7_sLh6FbpW5-aeQJgUG7lFSzWxmJdh74xq2/s320/P5030159.JPG" width="320" /></a></div>
<br />
<br />
<br />
<b> lisälukemista:</b>
<br />
Lestrup. T. 2008, Tutti frutti – Kaiken maailman hedelmät tutuiksi, Karisto Oy:n kirjapaino, Hämeenlinna 2008
<br />
<a href="http://Health benefits of passion fruit Delicious, passion fruit is a rich source of antioxidants, minerals, vitamins, and fiber. 100 g fruit contains about 97 calories. The fruit is an excellent source of dietary fiber. 100 g fruit pulp contains 10.4 g or 27% of fiber. A good fiber in the diet helps remove cholesterol from the body. Being a good bulk laxative, it also helps protect the colon mucosa by decreasing exposure time to toxic substances in the colon and wiping off the cancer-causing toxic substances from the colon. Passion fruit is good in vitamin-C, providing about 30 mg per 100 g. Vitamin-C (ascorbic acid) is a powerful water-soluble antioxidant. Consumption of fruits rich in vitamin-C helps the human body develop resistance against flu-like infectious agents and scavenge harmful, pro-inflammatory free radicals. The fruit carris very good levels of vitamin-A (provides about 1274 IU per 100 g), and flavonoid antioxidants such as ß-carotene and cryptoxanthin-ß. Current research studies suggest that these compounds have antioxidant properties, and along with vitamin-A are essential for good eyesight. Vitamin-A also required for maintaining healthy mucosa and skin. Consumption of natural fruits rich in vitamin-A and flavonoids may help to protect from lung and oral cavity cancers. Fresh granadilla is very rich in potassium. 100 g fruit pulp has about 348 mg of potassium. Potassium is a major component of cells and body fluids and helps regulate heart rate and blood pressure. Furthermore, granadilla is an excellent source of minerals. Iron, copper, magnesium and phosphorus are present in adequate amounts in the fruit.">http://fi.wikipedia.org/wiki/Punapassio </a><br />
<br />
http://www.kasvikset.fi/WebRoot/1033640/Oletussivu.aspx?id=1050835<br />
<br />
http://kuuyrttitarhassa.blogspot.fi/2012/03/intohimoinen-passionhedelma.html<br />
<br />
http://ruoka.fi/reseptit/helppo-kerrosherkku-mangosta-granaattiomenasta-ja-passiohedelmasta
<br />
http://www.healwithfood.org/health-benefits/passion-fruit-seeds.php<br />
<br />
<a href="http://www.nutrition-and-you.com/passion-fruit.html">http://www.nutrition-and-you.com/passion-fruit.html</a><br />
Health benefits of passion fruit<br />
<ul>
<li>
Delicious, passion fruit is a rich source of antioxidants, minerals,
vitamins, and fiber. 100 g fruit contains about 97 calories.<br />
</li>
<li>
The fruit is <b>an excellent source of dietary fiber</b>. 100 g fruit pulp
contains 10.4 g or 27% of fiber. A good fiber in the diet helps remove
cholesterol from the body. Being a good bulk laxative, it also helps
protect the colon mucosa by decreasing exposure time to toxic substances
in the colon and wiping off the cancer-causing toxic substances from
the colon.
<br />
</li>
<li>
Passion fruit is good in <b>vitamin-C</b>, providing about 30 mg per
100 g. Vitamin-C (ascorbic acid) is a powerful water-soluble
antioxidant. Consumption of fruits rich in vitamin-C helps the human
body develop resistance against flu-like infectious agents and scavenge
harmful, pro-inflammatory free radicals.
<br />
</li>
<li>
The fruit carries very good levels of <b>vitamin-A</b> (provides about
1274 IU per 100 g), and flavonoid antioxidants such as
ß-carotene and cryptoxanthin-ß. Current research studies suggest that
these compounds have antioxidant properties, and along with vitamin-A
are essential for good eyesight.<br />
</li>
<li>
Vitamin-A also required for maintaining healthy mucosa and skin.
Consumption of natural fruits rich in vitamin-A and flavonoids may help
to protect from lung and oral cavity cancers.<br />
</li>
<li>
Fresh granadilla is very rich in potassium. 100 g fruit pulp has
about 348 mg of potassium. Potassium is a major component of cells and
body fluids and helps regulate heart rate and blood pressure. <br />
</li>
<li>
Furthermore, granadilla is an excellent source of minerals. Iron,
copper, magnesium and phosphorus are present in adequate amounts in the
fruit. <br />
</li>
</ul>
<br />
<br />
<br />
<a href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub">https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub</a><br />
<h4 class="Head">
<span class="title-text">Evaluation of the antioxidant activity of passion fruit (<i>Passiflora edulis</i> and <i>Passiflora alata</i>) extracts on stimulated neutrophils and myeloperoxidase activity assays</span></h4>
<div class="Banner" id="banner">
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<span class="sr-only">Author links open overlay panel</span><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id5"><span class="content"><span class="text given-name">Maria Luiza</span><span class="text surname">Zeraik</span><span class="author-ref" id="baff1"><sup>a</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id6"><span class="content"><span class="text given-name">Didier</span><span class="text surname">Serteyn</span><span class="author-ref" id="baff2"><sup>b</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id7"><span class="content"><span class="text given-name">Ginette</span><span class="text surname">Deby-Dupont</span><span class="author-ref" id="baff2"><sup>b</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id8"><span class="content"><span class="text given-name">Jean-Nöel</span><span class="text surname">Wauters</span><span class="author-ref" id="baff3"><sup>c</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id9"><span class="content"><span class="text given-name">Monique</span><span class="text surname">Tits</span><span class="author-ref" id="baff3"><sup>c</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id10"><span class="content"><span class="text given-name">Janete H.</span><span class="text surname">Yariwake</span><span class="author-ref" id="baff1"><sup>a</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id11"><span class="content"><span class="text given-name">Luc</span><span class="text surname">Angenot</span><span class="author-ref" id="baff3"><sup>c</sup></span></span></a><a class="author size-m workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#!" name="baep-author-id12"><span class="content"><span class="text given-name">Thierry</span><span class="text surname">Franck</span><span class="author-ref" id="baff2"><sup>b</sup></span><svg class="icon icon-person" height="24" viewbox="0 0 106 128" width="19.875"></svg></span></a></div>
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<h2>
1. Introduction</h2>
<div id="p0005">
Polymorphonuclear neutrophils
(PMN) are specialised for their primary function of phagocytosis, with
highly developed mechanisms for intracellular digestion of particles,
such as pathogens and cell debris. However, excessive activation of PMN
generates reactive oxygen species (ROS). In addition to producing ROS,
neutrophil granules discharge hydrolytic and proteolytic enzymes, which
are implicated in several human and animal diseases, such as
neurodegenerative disorders, cancer, cardiovascular diseases,
atherosclerosis, cataracts, DNA damage and inflammation, etc. (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0005" name="bb0005">Babior, 2000</a>, <a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0075" name="bb0075">Klebanoff, 2005</a>).</div>
<div id="p0010">
Myeloperoxidase
(MPO), a specific granular enzyme of PMN, is considered as a marker of
stimulated PMN and contributes to oxidative stress by generating oxidant
species, particularly hypochlorous acid (HOCl), an important microbial
killer through both oxidation and chlorination reactions (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0040" name="bb0040">Deby-Dupont et al., 1999</a>, <a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0155" name="bb0155">Serteyn et al., 2003</a>).
MPO is released in the extracellular medium by highly stimulated and
dying neutrophils in pathological conditions of acute and chronic
inflammation. Under these conditions, MPO is able to exert oxidant
activity on neighbouring cells and tissues (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0075" name="bb0075">Klebanoff, 2005</a>).</div>
<div id="p0015">
<b>Many
molecules, such as phenolic compounds</b>, are known to possess <b>antioxidant
activity </b>that <b>inhibits oxidative damage and may consequently prevent
inflammatory conditions</b> (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0070" name="bb0070">Khanna et al., 2007</a>), ageing and neurodegenerative diseases (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0060" name="bb0060">Fusco, Colloca, Monaco, & Cesari, 2007</a>). Recent studies have focused on <b>the health effects of phenols, including flavonoids from fruit and vegetables </b>(<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0035" name="bb0035">Conforti et al., 2009</a>, <a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0175" name="bb0175">Vila et al., 2008</a>). Phenolic compounds are present in many plants, such as <b><i>Passiflora edulis</i></b> and <b><i>Passiflora alata</i>,</b> mainly belonging to the<b> flavones <i>C</i>-glucoside class</b> (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0045" name="bb0045">Dhawan, Dhawan, & Sharma, 2004</a>). <b>Isoorientin </b>(<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#f0005" name="bf0005">Fig. 1</a>), a <i>C</i>-glucoside flavone found in <i>P. edulis</i> (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0045" name="bb0045">Dhawan et al., 2004</a>), was also found to be the major flavonoid in pulp extracts of this species. In fact, the total flavonoid content in <i>P. edulis</i>
pulp was reported to be quite significant in comparison with other
beverages that are sources of flavonoids, such as orange juice and
sugarcane juice (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0180" name="bb0180">Zeraik & Yariwake, 2010</a>).</div>
<div id="p0015">
<br /></div>
<div id="p0020">
The aforementioned <b><i>Passiflora</i> species</b> are widely cultivated and consumed in Brazil: <i>P. edulis</i> pulp is used mainly in the industrial production of juice, while <i>P. alata</i> is typically consumed fresh due to its sweeter taste (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0020" name="bb0020">Carvalho-Okano & Vieira, 2001</a>).
<b>Passion fruit rind,</b> the main by-product of the juice industry, contains
<b>pectin</b>, a highly valued functional food ingredient widely used as a
gelling agent and stabiliser (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0135" name="bb0135">Pinheiro et al., 2008</a>). These rinds have also been studied for use in the production of candy and flour for human consumption (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0145" name="bb0145">Ramos et al., 2007</a>).
Due to its high nutritional value and flavonoid contents,
investigations to evaluate the potential of passion fruit as a
<b>functional food </b>or a<b> source of active compounds for antioxidant</b> or<b>
anti-inflammatory purposes</b> are very important. Moreover, although
agroindustrial by-products may be rich sources of bioactive compounds (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0010" name="bb0010">Balasundram, Sundram, & Samman, 2006</a>), the use of passion fruit rinds still requires further studies.</div>
<div id="p0020">
<br /></div>
<div id="p0025">
Recent
studies have shown the potential of <b>passion fruit and its rind</b> for
several purposes, such as the <b>antihypertensive effect </b>of passion fruit
rind attributed partially to the <b>vasodilatory effect</b> of polyphenols,
especially the flavonoid <b>luteolin</b> (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0065" name="bb0065">Ichimura et al., 2006</a>).
However, the pulp biological activity that has been the most
extensively studied is its antioxidant activity, using various methods,
such as DPPH, FRAP, ABTS and DMPD (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0095" name="bb0095">Kuskoski et al., 2005</a>, <a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0170" name="bb0170">Vasco et al., 2008</a>).
These methods explore mainly the stoichiometric activity of extracts by
measuring the ability of polyphenolic molecules to trap or neutralise
radical species generated by <i>in vitro</i> molecular models. Some <i>in vivo</i> studies have detected anti-inflammatory activity of <b><i>P. edulis</i> and <i>P. alata</i> leaves </b>(<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0165" name="bb0165">Vargas et al., 2007</a>, <a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0185" name="bb0185">Zucolotto et al., 2009</a>)
by using a carrageenan-induced pleurisy model in mice. These studies
showed a decrease of MPO activity, which was associated with a decrease
of neutrophil influx. However, the effect of these extracts on ROS
produced by stimulated neutrophils and on the true enzymatic activity of
MPO, considered as a target for new drug development (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0120" name="bb0120">Malle, Furtmuller, Sattler, & Obinger, 2007</a>) has not been studied.</div>
<div id="p0025">
<br /></div>
<div id="p0025">
The originality of this work was to study <b>the antioxidant activities of
passion fruit extra</b>cts in a model that distinguishes between two
important aspects of the antioxidant activity of a molecule or an
extract, either its stoichiometric activity of ROS trapping or its
anticatalytic activity by blocking the active site of an
oxidant-producing enzyme. In the present study, we assessed the
antioxidant activities on phorbol myristate acetate-stimulated equine
neutrophils and on purified equine MPO of dry methanol extracts from raw
pulp of <i>P. alata</i> and <i>P. edulis</i> and also from the rind of <i>P. edulis</i> fruit infected or not with the passion fruit woodiness virus (PWV) (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0160" name="bb0160">Trevisan et al., 2006</a>).
The stoichiometric effect of the extracts on the production of ROS by
PMN was measured by lucigenin-enhanced chemiluminescence (CL), while the
anticatalytic effect on the activity of purified MPO was evaluated by
SIEFED (Specific Immunological Extraction Followed by Enzymatic
Detection), a method whereby the drug interaction with the enzyme can be
studied without interference from the reaction medium (<a class="workspace-trigger" href="https://www.sciencedirect.com/science/article/pii/S0308814611003670?via%3Dihub#b0050" name="bb0050">Franck et al., 2006</a>). Additionally, the isoorientin content in the extracts was determined by HPLC–UV/DAD.</div>
<div id="p0025">
....</div>
<br />
<br />
<br />
<section id="s0070">4. Conclusions<br />
<div id="p0145">
<b><i>P. edulis</i> rinds </b>exhibited a higher activity than <b><i>P. alata</i></b>
towards the oxidant response of equine PMN, including ROS production
and MPO activity. This antioxidant activity was correlated with the
<b>isoorientin</b> content in the <b><i>P. edulis</i> extracts</b>, and suggests
that the passion fruit rinds – a by-product of the passion fruit
processing industry – are a possible source of natural antioxidants that
should be more carefully evaluated. In addition, the combination of the
neutrophil and the myeloperoxidase models, both cells and enzyme
playing important roles in ROS and radical species production, appears
as an efficient tool to detect and distinguish between the
stoichiometric and anticatalytic antioxidant activities of natural
compounds with potential therapeutic effects on oxidant stress and
inflammation.<br />
<br />
<br />
<br />
<figure class="figure" id="f0005"><img alt="" height="131" src="https://ars.els-cdn.com/content/image/1-s2.0-S0308814611003670-gr1.jpg" /><ol class="links-for-figure">
<li><a class="anchor download-link" href="https://ars.els-cdn.com/content/image/1-s2.0-S0308814611003670-gr1.jpg" target="_blank" title="Download full-size image"><span class="anchor-text">Download full-size image</span></a></li>
</ol>
<div class="captions">
<br />
<div id="sp015">
<span class="label">Fig. 1</span>. Structure of the flavone isoorientin and Glu: glucose.</div>
</div>
</figure></div>
</section><br />
<div id="p0015">
<br /></div>
</div>
</div>
Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-85829806634560013182018-10-31T11:57:00.000+01:002018-10-31T12:03:12.295+01:00Kiwi ( Kiivihedelmä) Actinidia sp. Actinidiaceae Tämän
heimon ensimmäinen kasvi oli KIWI- hedelmä. Siteeraan tietoa mitä
löydän:<br />
<br />
<div class="western">
ACTINIDIACEAE (laikkuköynnökset) </div>
<div class="western">
<b>Actinidia
kolomikta,</b></div>
<div class="western">
<b> ruots. kameleontbuske </b><b><b>(Sommargröna
lignos, klätterväxter)</b></b></div>
<div class="western">
<b><b> </b>suom. KIINANLAIKKUKÖYNNÖS </b></div>
<ol><div style="line-height: 100%; margin-bottom: 0cm;">
(729)
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Actinidiaceae">https://www.ncbi.nlm.nih.gov/pubmed/?term=Actinidiaceae</a></div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<a href="https://fi.wikipedia.org/wiki/Kiinanlaikkuk%C3%B6ynn%C3%B6s">https://fi.wikipedia.org/wiki/Kiinanlaikkuk%C3%B6ynn%C3%B6s</a></div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<a href="https://sv.wikipedia.org/wiki/Kameleontbuske">https://sv.wikipedia.org/wiki/Kameleontbuske</a></div>
</ol>
<ol start="0"><div style="line-height: 100%; margin-bottom: 0cm;">
Esimerkki tämän heimon kasivsta on KIINANLAIKKUKÖYNNÖS. Sen
ruotsalainen nimi on kameleonttipuska, Kameleontbuske. Sen kesävihanta
lignoosi , kiipeävä köynnöskasvi<b><br /></b></div>
<div style="line-height: 100%; margin-bottom: 0cm;">
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
Löydän sille netistä monta synonyymiä-</div>
</ol>
<div style="line-height: 100%; margin-bottom: 0cm;">
<a href="https://www.blogger.com/null" name="Synonymer"></a></div>
<div style="line-height: 100%; margin-bottom: 0cm;">
var. <i>gagnepainii</i>
(Nakai) H.L.Li
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Actinidia
gagnepainii</i> Nakai</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
var. <i>kolomikta</i>
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i><b>Actinidia
kolomikta</b></i><b> </b>var. <i>shihmienensis</i> C.Y.Chang
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Actinidia
leptophylla</i> C.Y.Wu
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Actinidia
maloides</i> Li
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Actinidia
maloides</i> f. <i>cordata</i> C.F.Liang
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Actinidia
tetramera</i> var. <i>maloides</i> (H.L.Li) C.Y.Wu
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Kalomikta
mandshurica</i> Regel ex Maxim. <a href="https://sv.wikipedia.org/wiki/Nom._illeg.">nom.
illeg.</a>
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Prunus kolomikta</i>
Maxim. & Ruprecht
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
<i>Trochostigma
kolomikta</i> (Maximowicz & Ruprecht) Rupreccht</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
PubMed hakulaitetella <b>Actinidiaceae- heimosta</b> löytyy yli 700
artikkelia. Silmäilen niistä jotqin olennaista tietoa esiin. Myös <b>KIWI
hedelmä
</b> kuuluu tähän lajiin. Siitä on eräs tieteellinen artikkeli. </div>
<div style="line-height: 100%; margin-bottom: 0cm;">
</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
Suomennosta.</div>
<div style="line-height: 100%; margin-bottom: 0cm;">
" <b>KIWI -hedelmä,</b> <b>Actinia chinensis,</b> on geneettisesti
sekvensoitu ja se on Actinidaceae- heimon ensimmäinen jäsen. Sen
geenihistoriassa huomataan jälkeä polyploidisoitumistapahtumista, joita
on ollut vaikea kartoittaa. Tässä artikkelissa tutkijat esittävät uuden
analysoinnin sen genomista ja ha havaitsivat näyttöä kahdesta
tetraplodisoitumistapahtumasta, joista toinen oli 50- 57 miljoonaa
vuotta sitten ja toinen noin 18- 20 miljoonaa vuotta sitten. Kaksi
genomista alaryhmää ovat olleet tasapainoisessa fraktionaatiossa.
Lisäksi on havaittu geenien ilmenevän tasapainoisella tavalla
kromosomiduplikaatiokopioiden suhteen. Kiwihedelmän geeneissä on
havaittu alentunutta evolutionaalista tahtia. Nämä havainnot
voisivat selittyä polyploidisoitumistapahtumien todennäköisestä
autotetraploidisaatioluonteesta. Lisäksi tutkijat havaitsivat, että
polyploidisaatio vaikutti osaltaan avainasemassa olevien
funktionaalisten geenien kuten esim. C-vitamiinin biosynteesin geenien
laajenemiseen. Tutkijoiden työ suo myös tärkeää vertailevaa genomista
tietoa Actinidaceae heimosta ja sen kaltaiasista heimoista". </div>
<div style="line-height: 100%; margin-bottom: 0cm;">
</div>
<ul>
<li><i>The genome of
<b>kiwifruit (Actinidia chinensis)</b> was sequenced previously, <b>the
first in the</b> <b>Actinidiaceae family.</b> It was shown to have
been affected by polyploidization events, the nature of which has
been elusive. Here, we performed a reanalysis of the genome and found
clear evidence of 2 tetraploidization events, with one occurring
∼50-57 million years ago (Mya) and the other ∼18-20 Mya. Two
subgenomes produced by each event have been under balanced
fractionation. Moreover, genes were revealed to express in a balanced
way between duplicated copies of chromosomes. Besides, lowered
evolutionary rates of kiwifruit genes were observed. These findings
could be explained by the likely auto-tetraploidization nature of the
polyploidization events. Besides, we found that polyploidy
contributed to the expansion of key functional genes, e.g., vitamin C
biosynthesis genes. The present work also provided an important
comparative genomics resource in the Actinidiaceae and related
families.</i></li>
</ul>
www.Fineli.fi antaa tietoa jonkin <b> Kiwi- eli kiivihedelmäsortin </b> C-vitamiinipitoisuudesta.<br />
<br />
<a href="https://fineli.fi/fineli/fi/elintarvikkeet?q=kiivi&foodType=ANY"> https://fineli.fi/fineli/fi/elintarvikkeet?q=kiivi&foodType=ANY</a><br />
100 g kuorittua kiivihedelmää antaa 67 mg C-vitamiinia, mikä kattaa
hyvin vähimmän ehdottomasti vaadittavan päivätarpeen 10 mg.
Keskimääräinen C-vitamiinitarpe miehillä on 60 mg ja naisilla 50 mg.
Suositus NNR 2012 on kuitenkin miehille ja naisille 75 mg C-
vitamiinia päivässä, joten kiivihedelmästa sellaiseen määrään pääsee
noin 120 grammalla kuorittua Kiwihedelmää. Jos syö hedelmän
kuorineen tarvitsee syödä muutaman gramman enemmän jotta yltää
tuohon C-vitamiinimäärään ( 121 grammaa kiivihedelmää).<br />
Kiwihedelmästä (100g) saa K-vitamiinia 34 mikrogrammaa. Kaliumia saa noin 290 grammaa.<br />
Kirpeä maku kiivihedlmässä johtuu sen orgaanisista hapoista , joita on 2.5 grammaa / 100 grammaa. <br />
<b><br /></b>
<b>Japanilaiset ovat tutkineet tarkasti kiivihedelmien (Actinia arguta ) terveydellisiä etuja. </b><br />
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717121/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717121/</a><br />
Jos vertaan näitä tietoja suomaliseen elintarviketietueeseen, täytyy
päätellä että kiivilaatu,jota japanilaiset käyttävät "kiivimarja" on
eri kuin se minkä suomalaiset ovat analysoineet. Heidän analyysinsä
antaa 450 mg C-vitamiinia 100 grammassa tuoretta kiivimarjaa. Lisäksi
myo-inositolilähteenä he amintisevat tämän kiivimarjan erinomaisena. Se
voisi olla hyödyksi luuston kohentamiseen, koska se antaa <b>myo-inositolia</b>
( molekyyliä, joka voi kantaa runsaasti fosfaatteja, jotka
inositolirungossa ollen ovat orgaanisia. 982 mg myoinositolia / 100g
tuoretta kiivimarjaa. Lisäksi siinä on runsaasti <b>fenolisia antioksidantteja</b> 1301 mg/ 100 g. Siinä on lisäksi <b>luteiinia</b>,
joka on silmänpohjalle edullinen molekyyli. Myös essentieleljä
mineraaleja mainitaan: kalium, kalsium, sinkki. Sen monet hyvät
ominaisuudet liittävät sen terveysruokiin. Artikkeli mainitsee kolme
lajia: <b>A.arguata, A. kolomikta ja A.polygama</b>. Niitä sanotaan myös
anti-inflammatorisiksi vaikutukseltaan ( kun kyse ei ole allergisesta
tulehduksesta). Siis kaikin puolin Pohjolan ihmisille suositeltava
kaamoksen ajan hedelmä. <br />
<ul>
<li><b> The kiwiberry (<i>Actinidia arguta</i>)</b> is a new product on the market
that is enjoying growing consumer acceptance around the world. This
widespread interest has created increased demand for identification of
the kiwiberry’s nutritional health benefits. Containing over 20
essential nutrients and a range of vitamins, the <b>kiwiberry</b> comes near
the top of fruits classed as superfoods. It is one of the richest
sources of vitamin C with up to <b>430 mg/100 g</b> fresh weight (FW) and is
considered the richest dietary source of <b><i>myo</i>-inosito</b>l (up to
<b>982 mg/100 g</b> FW). The kiwiberry is also one of the richest sources of
<b>lutein</b> (up to 0.93 mg/100 g FW) in commonly consumed fruit. Furthermore,
containing up to 1301.1 mg/100 g FW phenolics and significant amounts
of the essential minerals of potassium, calcium and zinc, the kiwiberry
rates very highly as a ‘healthy food’.<b> The type and number of this
fruit’s medicinally promising nutrients have motivated ongoing
investigations into its antioxidant, anti-tumour and anti-inflammatory
properties</b>. Early research has pointed to the kiwiberry being a very
promising treatment for some cancers and health issues involving the
gastrointestinal system, hypercholesterolemia and certain cancers. A
pharmaceutical composition of <i>A. arguta</i>, <i>A. kolomikta</i>, and <i>A. polygama</i>
extracts has already been registered for the prevention and treatment
of some immune (inflammatory) mediated diseases, as well as the
treatment of some non-allergic inflammatory diseases. This paper reviews
and highlights the limited nutritional and therapeutic information
currently available on the kiwiberry, a minor fruit possessing such
major properties.</li>
</ul>
Muistiin 31.10.2018 Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-48939573227182209732018-08-03T12:43:00.001+02:002018-08-03T12:43:18.958+02:00Probioottiset meloni ja cashew juissit <a href="https://www.ncbi.nlm.nih.gov/pubmed/28784506">https://www.ncbi.nlm.nih.gov/pubmed/28784506</a><br />
<br />
<div class="cit">
<span role="menubar"><a href="https://www.ncbi.nlm.nih.gov/pubmed/28784506#" role="menuitem" title="Food research international (Ottawa, Ont.).">Food Res Int.</a></span> 2017 Sep;99(Pt 1):461-468. doi: 10.1016/j.foodres.2017.05.030. Epub 2017 May 30.</div>
<b>Chemometric evaluation of the volatile profile of probiotic melon and probiotic cashew juice.</b><br />
<div class="auths">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=de%20Godoy%20Alves%20Filho%20E%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">de Godoy Alves Filho E</a><sup>1</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Rodrigues%20THS%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">Rodrigues THS</a><sup>2</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Fernandes%20FAN%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">Fernandes FAN</a><sup>3</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Pereira%20ALF%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">Pereira ALF</a><sup>4</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Narain%20N%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">Narain N</a><sup>5</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=de%20Brito%20ES%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">de Brito ES</a><sup>2</sup>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Rodrigues%20S%5BAuthor%5D&cauthor=true&cauthor_uid=28784506">Rodrigues S</a><sup>6</sup>.</div>
<div class="abstr">
<h3>
Abstract</h3>
<div class="">
The
aim of this study was <b>to evaluate the influence of the lactic acid
fermentation</b> on volatile compounds of melon and cashew apple juices. The
effect of the fermentation processing on the volatile profile of
probiotic juices was assessed by HS-SPME/GC-MS coupled to chemometrics
with 67.9% and 81.0% of the variance in the first principal component
for melon and cashew juices, respectively.<br />
<br />
<b> The Lactobacillus casei
fermentation</b> imparted a reduction of ethyl butanoate,
ethyl-2-methylbutirate, and ethyl hexanoate for <b>melon juice;</b> and of
ethyl acetate, ethyl-2-methyl butanoate, ethyl <span class="highlight">crotonate</span>,
ethyl isovalerate, benzaldehyde, and ethyl hexanoate for<b> cashew juice</b>.
Measurements of the stability of these compounds and the formation of
the component 3-methyl-2-butenyl in melon juice may be used as a
volatile marker to follow the juice fermentation.<br />
<br />
These findings
suggested that even though it is not a dairy product the lactic acid
fermentation of fruits developed a volatile profile combining the fruit
and lactic acid fermentation volatiles with mildly formation or
degradation of aroma compounds.</div>
</div>
<div class="keywords">
<h4>
KEYWORDS: </h4>
Anacardium occidentale; Chemometrics; Cucumis melo; HS-SPME/GC–MS; Lactic acid fermentation</div>
<div class="resc">
<dl class="rprtid">
<dt>PMID:</dt>
<dd>28784506</dd>
<dt>DOI:</dt>
<dd><a href="https://doi.org/10.1016/j.foodres.2017.05.030" target="_blank">10.1016/j.foodres.2017.05.030</a></dd></dl>
</div>
Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-82023984982260761992018-05-18T09:33:00.003+02:002018-05-18T09:33:41.829+02:00Isokversetiini <a href="https://en.wikipedia.org/wiki/Isoquercetin">https://en.wikipedia.org/wiki/Isoquercetin</a><br />
Flavonoidi jota on mm. mangohedelmässä. Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0tag:blogger.com,1999:blog-5053133206211396187.post-13563198919415303962018-03-24T10:13:00.002+01:002018-03-24T10:45:08.160+01:00Rosmariiniöljy - mitä tämä sisältää? <a href="https://www.ncbi.nlm.nih.gov/pubmed/29348107">https://www.ncbi.nlm.nih.gov/pubmed/29348107</a><br />
<br />
<a href="https://phytochem.nal.usda.gov/phytochem/plants/show/1719?qlookup=Rosmarinus+officinalis&offset=0&max=20&et=">https://phytochem.nal.usda.gov/phytochem/plants/show/1719?qlookup=Rosmarinus+officinalis&offset=0&max=20&et=</a><br />
<br />
Rosmariinin öljyn osatekijöitä: <br />
https://phytochem.nal.usda.gov/phytochem/plants/show/1719?qlookup=Rosmarinus+officinalis&offset=0&max=20&et=<a href="https://phytochem.nal.usda.gov/phytochem/plants/show/1719?qlookup=Rosmarinus+officinalis&offset=0&max=20&et=">https://phytochem.nal.usda.gov/phytochem/plants/show/1719?qlookup=Rosmarinus+officinalis&offset=0&max=20&et=</a><br />
<ul>
<li>18CINEOL eli eukalyptol</li>
</ul>
https://sv.wikipedia.org/wiki/Eukalyptol<br />
<br />
<span class="mw-headline" id="Pharmakologische_Wirkungen">(saksalainen selitys) Pharmakologische Wirkungen</span><br />
1,8-Cineol wirkt beim Menschen in der <a href="https://de.wikipedia.org/wiki/Lunge" title="Lunge">Lunge</a> und den <a class="mw-redirect" href="https://de.wikipedia.org/wiki/Nebenh%C3%B6hle" title="Nebenhöhle">Nebenhöhlen</a> schleimlösend und <a href="https://de.wikipedia.org/wiki/Bakterizid" title="Bakterizid">bakterizid</a>. Außerdem hemmt es bestimmte <a href="https://de.wikipedia.org/wiki/Neurotransmitter" title="Neurotransmitter">Neurotransmitter</a>, die für die Verengung der Bronchien verantwortlich sind. Bei <a class="mw-redirect" href="https://de.wikipedia.org/wiki/Asthma" title="Asthma">Asthmatikern</a> kann unter ärztlicher Kontrolle durch Gabe von reinem Cineol die Lungenfunktion verbessert werden.<sup class="reference" id="cite_ref-RL_9-0"><a href="https://de.wikipedia.org/wiki/1,8-Cineol#cite_note-RL-9">[9]</a></sup><sup class="reference" id="cite_ref-10"><a href="https://de.wikipedia.org/wiki/1,8-Cineol#cite_note-10">[10]</a></sup> Cineol stellt jedoch nur in Ausnahmefällen eine Alternative zu <a href="https://de.wikipedia.org/wiki/Corticosteroide" title="Corticosteroide">Corticosteroiden</a> dar, die als <a href="https://de.wikipedia.org/wiki/Inhalation" title="Inhalation">Inhalation</a>
örtlich und nebenwirkungsarm angewandt werden können. Auch bei der
chronisch-obstruktiven Lungenerkrankung COPD kann reines Cineol als
Zusatzmedikation zur Standardtherapie unter Umständen die Lungenfunktion
verbessern und auf diese Weise <a href="https://de.wikipedia.org/wiki/Exazerbation" title="Exazerbation">Exazerbationen</a> reduzieren.<sup class="reference" id="cite_ref-11"><a href="https://de.wikipedia.org/wiki/1,8-Cineol#cite_note-11">[11]</a></sup>
<br />
Von 1,8-Cineol sind als <a href="https://de.wikipedia.org/wiki/Nebenwirkung" title="Nebenwirkung">Nebenwirkungen</a> leichte <a href="https://de.wikipedia.org/wiki/Kot" title="Kot">Stuhlverflüssigung</a> und eventuell leichte <a href="https://de.wikipedia.org/wiki/%C3%9Cbelkeit" title="Übelkeit">Übelkeit</a> bekannt. Beides tritt nur bei <a href="https://de.wikipedia.org/wiki/Peroral" title="Peroral">oraler</a> Einnahme auf. Weiterhin wurden – vor allem bei Kindern – auch allergische Reaktionen<sup class="reference" id="cite_ref-12"><a href="https://de.wikipedia.org/wiki/1,8-Cineol#cite_note-12">[12]</a></sup> beschrieben. Die Einnahme erfolgt durch orale Zufuhr von Kapseln, die sich erst im <a href="https://de.wikipedia.org/wiki/D%C3%BCnndarm" title="Dünndarm">Dünndarm</a> auflösen, durch <a class="mw-redirect" href="https://de.wikipedia.org/wiki/Inhalieren" title="Inhalieren">Inhalation</a> oder durch Zubereitung entsprechender den Wirkstoff enthaltender Pflanzen als <a href="https://de.wikipedia.org/wiki/Aufguss_(Zubereitung)" title="Aufguss (Zubereitung)">Aufguss</a>.<br />
<br />
<ul>
<li> LIMONENE</li>
</ul>
https://sv.wikipedia.org/wiki/Limonen<br />
<br />
<ul>
<li> OCIMENE</li>
</ul>
https://en.wikipedia.org/wiki/Ocimene<br />
https://de.wikipedia.org/wiki/Ocimene<br />
<br />
<ul>
<li>BASILICUM OIL </li>
</ul>
https://de.wikipedia.org/wiki/Basilikum%C3%B6l<br />
<br />
<br />
OCINUM CANUM<br />
<a href="https://www.sciencedirect.com/science/article/pii/S1319610312000026">https://www.sciencedirect.com/science/article/pii/S1319610312000026</a><br />
<br />
OCINUM lajeja:<br />
basilikasuku<br />
<br />
https://sv.wikipedia.org/wiki/Kransblommiga_v%C3%A4xter<br />
<br />Kirjallisuuttahttp://www.blogger.com/profile/16148723032772961328noreply@blogger.com0