Molecules. 2020 Mar 24;25(6). pii: E1456. doi: 10.3390/molecules25061456.
Interaction of Catechins with Human Erythrocytes.
Abstract
The
aim of this study was to characterize the interaction of chosen
catechins ((+)-catechin, (-)-epigallocatechin (EGC), and
(-)-epigallocatechin gallate (EGCG))
with human erythrocytes and their protective effects against oxidative
damage of erythrocytes. Uptake of the catechins by erythrocytes was
studied by fluorimetry, their interaction with erythrocyte membrane was
probed by changes in erythrocyte osmotic fragility and in membrane
fluidity evaluated with spin labels, while protection against oxidative
damage was assessed by protection against hemolysis induced by
permanganate and protection of erythrocyte membranes against lipid
peroxidation and protein thiol group oxidation. Catechin uptake was
similar for all the compounds studied. Accumulation of catechins in the
erythrocyte membrane was demonstrated by the catechin-induced increase
in osmotic resistance and rigidification of the erythrocyte membrane
detected by spin labels 5-doxyl stearic acid and 16-doxyl stearic acid.
(-)-Epigallocatechin and EGCG
inhibited erythrocyte acetylcholinesterase (mixed-type inhibition).
Catechins protected erythrocytes against permanganate-induced hemolysis,
oxidation of erythrocyte protein thiol groups, as well as membrane
lipid peroxidation. These results contribute to the knowledge of the
beneficial effects of catechins present in plant-derived food and
beverages KEYWORDS:
(−)-epigallocatechin;
(−)-epigallocatechin gallate; antioxidant; catechin; erythrocyte;
hemolysis; membrane rigidity; monometric flavanols
Free full text Healthline- lähteestä sitaatti: " EGCG is most prevalent in green tea but also found in smaller quantities in other types of tea, fruit, and some nuts. Other health-promoting catechins are plentiful in red wine, dark chocolate, legumes, and most fruit."
Muuten, Ruotsin uutisissa puhuttiin tänään elintarviketiloanteen ehkä huononemisesta jopa hedelmien ja vihannesten osalta Euroopassa toimituksista johtuen. Sesonkityöntekijät eivät pääsee liikkumaan pandemiaolosuhteiden takia ja sadonkorjuut jäävät useissa Etelä-Euroopan maissa hoitumatta ehkä, jos ei omista kansalaisista tule sadonkorjuujoukkoja. Ruotsissa saataneen sadonkorjuuväkeä työnvälityksen kautta omastakin maasta. Sinänsä ei tällä hetkellä vaivaa kato-olosuhteet Eurooppaa , kuten Afrikassa heinäsirkkavitsauksen takia. Ainoastaan ihmisten rekrytoiminen sadonkorjuuseen ja valmiin olevaisen ja tulevaisen sadon käsittely ja kuljetus on nyt ongelmatasoa, joka riippuu ihmisestä eikä ilmasta tai eläimistä.
