Chemical constituents of fresh celery].
Zhongguo Zhong Yao Za Zhi
Zhongguo Zhong Yao Za Zhi 2009 Jun;34(12):1512-5
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To study the chemical constituents of the whole plant of fresh celery (Apium graveolens).
The constituents were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatography, PTLC, HPLC, and their structures were elucidated on the basis of spectral evidences.
Twenty compounds were obtained and identified as
falcariondiol (1),
(9Z) 1,9-heptadecadiene-4,6-diyne-3,8,11-triol (2),
oplopandiol (3),
bergapten (4),
5,8-dimethoxy psoralen (5),
isofraxidin (6),
eugenic acid (7),
trans-ferulic acid (8),
trans-cinnamic acid (9),
p-hydroxyphenylethanol ferulate (10),
caffeoylquinic acid (11),
5-p-trans-coumaroylquinic acid (12),
sedanolide (13),
lunularin (14),
lunularic acid (15),
2-(3-methoxy-4-hydroxyphenol)-propane-1,3-diol (16),
D-allitol (17),
beta-sitosterol (18),
benzolic acid (19),
succinic acid (20).
Compounds 2, 3, 6, 10, 12, 14-17 were isolated from genus Apium for the first time.
The constituents were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatography, PTLC, HPLC, and their structures were elucidated on the basis of spectral evidences.
Twenty compounds were obtained and identified as
falcariondiol (1),
(9Z) 1,9-heptadecadiene-4,6-diyne-3,8,11-triol (2),
oplopandiol (3),
bergapten (4),
5,8-dimethoxy psoralen (5),
isofraxidin (6),
eugenic acid (7),
trans-ferulic acid (8),
trans-cinnamic acid (9),
p-hydroxyphenylethanol ferulate (10),
caffeoylquinic acid (11),
5-p-trans-coumaroylquinic acid (12),
sedanolide (13),
lunularin (14),
lunularic acid (15),
2-(3-methoxy-4-hydroxyphenol)-propane-1,3-diol (16),
D-allitol (17),
beta-sitosterol (18),
benzolic acid (19),
succinic acid (20).
Compounds 2, 3, 6, 10, 12, 14-17 were isolated from genus Apium for the first time.
Affiliation
Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
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