Katekiinien eduista . Punasolujen osmoottisen resistenssin suojeleminen

https://www.ncbi.nlm.nih.gov/pubmed/32213847

Molecules. 2020 Mar 24;25(6). pii: E1456. doi: 10.3390/molecules25061456.

Interaction of Catechins with Human Erythrocytes.

Naparlo K¹, Bartosz G², Stefaniuk I³, Cieniek B³, Soszynski M⁴, Sadowska-Bartosz I¹.

Abstract

The aim of this study was to characterize the interaction of chosen catechins ((+)-catechin, (-)-epigallocatechin (EGC), and (-)-epigallocatechin gallate (EGCG)) with human erythrocytes and their protective effects against oxidative damage of erythrocytes. Uptake of the catechins by erythrocytes was studied by fluorimetry, their interaction with erythrocyte membrane was probed by changes in erythrocyte osmotic fragility and in membrane fluidity evaluated with spin labels, while protection against oxidative damage was assessed by protection against hemolysis induced by permanganate and protection of erythrocyte membranes against lipid peroxidation and protein thiol group oxidation. Catechin uptake was similar for all the compounds studied. Accumulation of catechins in the erythrocyte membrane was demonstrated by the catechin-induced increase in osmotic resistance and rigidification of the erythrocyte membrane detected by spin labels 5-doxyl stearic acid and 16-doxyl stearic acid. (-)-Epigallocatechin and EGCG inhibited erythrocyte acetylcholinesterase (mixed-type inhibition). Catechins protected erythrocytes against permanganate-induced hemolysis, oxidation of erythrocyte protein thiol groups, as well as membrane lipid peroxidation. These results contribute to the knowledge of the beneficial effects of catechins present in plant-derived food and beverages KEYWORDS:

(−)-epigallocatechin; (−)-epigallocatechin gallate; antioxidant; catechin; erythrocyte; hemolysis; membrane rigidity; monometric flavanols

DOI:

10.3390/molecules25061456

Free full text Healthline- lähteestä sitaatti:  
" EGCG is most prevalent in green tea but also found in smaller quantities in other types of tea, fruit, and some nuts. Other health-promoting catechins are plentiful in red wine, dark chocolate, legumes, and most fruit."


Muuten, Ruotsin uutisissa puhuttiin tänään elintarviketiloanteen ehkä huononemisesta  jopa  hedelmien ja vihannesten osalta Euroopassa toimituksista johtuen.  Sesonkityöntekijät eivät pääsee liikkumaan pandemiaolosuhteiden takia ja sadonkorjuut jäävät  useissa Etelä-Euroopan maissa hoitumatta ehkä, jos ei omista kansalaisista tule sadonkorjuujoukkoja.  Ruotsissa saataneen sadonkorjuuväkeä  työnvälityksen kautta omastakin maasta.   Sinänsä ei tällä hetkellä vaivaa kato-olosuhteet Eurooppaa , kuten Afrikassa  heinäsirkkavitsauksen takia.  Ainoastaan ihmisten rekrytoiminen sadonkorjuuseen ja  valmiin olevaisen ja tulevaisen  sadon käsittely ja kuljetus on nyt ongelmatasoa, joka riippuu ihmisestä eikä ilmasta tai eläimistä.